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Overdose of sodium bicarbonate (sodium bicarbonate 5% injection) may result in a severe degree of alkalosis which may be accompanied by hyperirritability or tetany. Should alkalosis result, the bicarbonate should be stopped and the patient managed according to the degree of alkalosis present. Severe alkalosis may be controlled by parenteral injections of calcium gluconate or an acidifying agent such as ammonium chloride.
Reactions which may occur because of the solution or the technique of administration include febrile response, infection at the site of injection, venous thrombosis or phlebitis extending from the site of injection, extravasation, and hypervolemia.
If an adverse reaction does occur, discontinue the infusion, evaluate the patient, institute appropriate therapeutic countermeasures and save the remainder of the fluid for examination if deemed necessary.
Read the Sodium Bicarbonate (sodium bicarbonate 5% injection) Side Effects Center for a complete guide to possible side effects
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Last reviewed on RxList: 9/16/2008
This monograph has been modified to include the generic and brand name in many instances.
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