Sodium Sulfacetamide and Sulfur Lotion
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Sodium Sulfacetamide 10% and Sulfur 5% lotion
The most widely accepted mechanism of action of sulfonamides is the Woods-Fildes theory which is based on the fact that sulfonamides act as competitive antagonists to para-aminobenzoic acid (PABA), an essential component for bacterial growth. While absorption through intact skin has not been determined, sodium sulfacetamide is readily absorbed from the gastrointestinal tract when taken orally and excreted in the urine, largely unchanged. The biological half-life has variously been reported as 7 to 12.8 hours.
Last reviewed on RxList: 1/29/2009
This monograph has been modified to include the generic and brand name in many instances.
Additional Sodium Sulfacetamide 10% and Sulfur 5% lotion Information
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