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Soliris

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Soliris

Soliris Patient Information Including Side Effects

Brand Names: Soliris

Generic Name: eculizumab (Pronunciation: E kue LIZ oo mab)

What is eculizumab (Soliris)?

Eculizumab is a monoclonal antibody. Eculizumab binds to proteins in the blood that can destroy red blood cells in people with genetic conditions that affect the natural defenses of red blood cells.

Eculizumab is used to prevent the breakdown of red blood cells in people with paroxysmal nocturnal hemoglobinemia (PNH).

Eculizumab is also used to treat a rare chronic blood disease called atypical hemolytic uremic syndrome (aHUS)

Eculizumab may also be used for purposes not listed in this medication guide.

What are the possible side effects of eculizumab (Soliris)?

Seek emergency medical attention or call your doctor right away if you notice any of these symptoms of meningitis:

  • headache and fever with nausea or vomiting;
  • high fever (103 degrees or higher), body aches, flu symptoms;
  • confusion, increased sensitivity to light; or
  • stiffness in your neck or back.

With your medication you will receive a Patient Safety Card listing the symptoms of meningococcal infection. Carry this card with you at all times.

Get emergency medical help if you have any of these signs of an allergic reaction: hives; chest pain, difficult breathing; feeling like you might pass out; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these side effects during or after your treatment with eculizumab:

  • pale or yellowed skin, dark colored urine, fever, confusion or weakness;
  • feeling light-headed or short of breath, rapid heart rate, trouble concentrating;
  • easy bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin;
  • pain or burning when you urinate;
  • swelling, rapid weight gain, urinating less or not at all;
  • sudden numbness or weakness, especially on one side of the body;
  • sudden severe headache, problems with vision, speech, or balance;
  • chest pain, sudden cough, wheezing, rapid breathing, coughing up blood;
  • pain, swelling, warmth, or redness in one or both legs; or
  • increased blood pressure (severe headache, blurred vision, buzzing in your ears, shortness of breath).

Common side effects may include:

  • mild headache;
  • nausea, vomiting, diarrhea;
  • back pain; or
  • cold symptoms such as stuffy nose, sneezing, sore throat.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the Soliris (eculizumab) Side Effects Center for a complete guide to possible side effects

What is the most important information I should know about eculizumab (Soliris)?

Eculizumab is used to prevent the breakdown of red blood cells in people with paroxysmal nocturnal hemoglobinemia (PNH).

You should not use this medication if you have bacterial meningitis or if you have not been vaccinated against meningitis. Tell your doctor if you have a fever or any type of infection.

Eculizumab affects your immune system, and using this medication may increase your risk of serious infection such as meningitis. You must be vaccinated against meningococcal infection at least 2 weeks before you start treatment with eculizumab. Even if you have been vaccinated in the past, you may need a booster dose.

Seek emergency medical attention or call your doctor right away if you notice any of these symptoms of meningitis: headache and fever with nausea or vomiting, high fever (103 degrees or higher), body aches, flu symptoms, confusion, increased sensitivity to light, stiffness in your neck or back.

With your medication you will receive a Patient Safety Card listing the symptoms of meningitis. Carry this card with you at all times.

Do not stop using eculizumab without first talking to your doctor. Stopping or interrupting your treatment could cause sudden and serious effects on your red blood cells.

Side Effects Centers
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Soliris - User Reviews

Soliris User Reviews

Now you can gain knowledge and insight about a drug treatment with Patient Discussions.

Here is a collection of user reviews for the medication Soliris sorted by most helpful. Patient Discussions FAQs

Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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