April 27, 2017
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Soma Compound with Codeine

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Soma Compound with Codeine

(carisoprodol, aspirin and codeine phosphate, USP) Tablets for Oral Use

WARNING: May be habit-forming.


Soma Compound with Codeine (carisoprodol, aspirin, and codeine phosphate tablets) (carisoprodol, aspirin, and codeine phosphate tablets, USP) is a fixed-dose combination product containing the following three products:

  • 200 mg of carisoprodol, a centrally-acting muscle relaxant
  • 325 mg of aspirin, an analgesic with antipyretic and anti-inflammatory properties
  • 16 mg of codeine phosphate, a centrally-acting narcotic analgesic.

It is available as a two-layered, white and yellow, oval-shaped tablet for oral administration.

Carisoprodol: Chemically, carisoprodol is N-isopropyl-2-methyl-2-propyl-1,3propanediol dicarbamate and its molecular formula is C12H24N2O4, with a molecular weight of 260.33. The structural formula of carisoprodol is:

Carisoprodol Structural Formula Illustration

Aspirin: Chemically, aspirin (acetylsalicyclic acid) is 2-(acetyloxy)-, benzoic acid and its molecular formula is C9H8O4, with a molecular weight of 180.16. The structural formula of aspirin is:

Aspirin Structural Formula Illustration

Codeine Phosphate: Chemically, codeine phosphate is 7,8-Didehydro-4,5α-epoxy-3methoxy-17-methylmorphinan-6α-ol phosphate (1:1) (salt) hemihydrate and its molecular formula is C18H24NO7P, with a molecular weight of 406.37. The structural formula of codeine phosphate is:

Codeine Phosphate Structural Formula Illustration

Other ingredients in the Soma Compound with Codeine (carisoprodol, aspirin, and codeine phosphate tablets) drug product are croscarmellose sodium, D&C Yellow #10, hypromellose, magnesium stearate, microcrystalline cellulose, povidine, sodium metabisulfite, starch, and stearic acid.

What are the possible side effects of aspirin, carisoprodol, and codeine (Soma Compound with Codeine)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using this medicine and call your doctor at once if you have a serious side effect such as:

  • runny nose, wheezing, trouble breathing;
  • easy bruising or bleeding;
  • bleeding from your rectum or blood in your stools, vomiting, weight loss, night-time stomach pain;
  • coughing up blood or vomit that looks like coffee grounds;
  • ringing in your...

Read All Potential Side Effects and See Pictures of Soma Compound with Codeine »

What are the precautions when taking carisoprodol, aspirin, and codeine (Soma Compound with Codeine)?

Before taking this medication, tell your doctor or pharmacist if you are allergic to codeine, carisoprodol, or aspirin; or to related medications such as meprobamate, tybamate, or mebutamate; or to other narcotic pain medications (such as morphine); or to nonsteroidal anti-inflammatory drugs-NSAIDs (such as ibuprofen); or to other salicylates (such as choline salicylate); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: asthma (including a history of worsening breathing with runny/stuffy nose after taking aspirin or other NSAIDs), growths in the nose...

Read All Potential Precautions of Soma Compound with Codeine »

Last reviewed on RxList: 3/7/2017
This monograph has been modified to include the generic and brand name in many instances.

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