Somatuline Depot

SOMATULINE® DEPOT
(lanreotide) Injection

Somatuline Depot

DRUG DESCRIPTION

Somatuline Depot (lanreotide) Injection 60, 90 and 120 mg is a prolonged-release formulation for deep subcutaneous injection containing the drug substance lanreotide acetate, a synthetic octapeptide with a biological activity similar to naturally occurring somatostatin, and water for injection.

Somatuline Depot is available as sterile, ready-to-use, pre-filled syringes containing lanreotide supersaturated bulk solution of 24.6% w/w lanreotide base.

Each syringe contains: Somatuline Depot 60 mg Somatuline Depot 90 mg Somatuline Depot 120 mg
Lanreotide acetate 79.8 mg 116.4 mg 155.5 mg
Water for injection 186.2mg 271.6 mg 363 mg

Lanreotide acetate is a synthetic cyclical octapeptide analog of the natural hormone, somatostatin. Lanreotide acetate is chemically known as [cyclo S-S]-3-(2-naphthyl)-D-alanyl- L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-valyl-L-cysteinyl-L-threoninamide, acetate salt. Its molecular weight is 1096.34 (base) and its amino acid sequence is:

SOMATULINE® DEPOT (lanreotide) Structural Formula Illustration

For appearance of the formulation, see Dosage Forms and Strengths.

What are the possible side effects of lanreotide (Somatuline Depot)?

Stop using lanreotide and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

  • slow or uneven heartbeats;
  • gallbladder problems (pain in your upper right stomach area with nausea and vomiting);
  • thyroid problems (may be detected by blood tests);
  • pale skin, weakness, easy bruising or bleeding;
  • low blood sugar (headache, confusion, drowsiness, weakness,...

Read All Potential Side Effects and See Pictures of Somatuline Depot »

Last reviewed on RxList: 12/12/2013
This monograph has been modified to include the generic and brand name in many instances.

A A A

Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


Women's Health

Find out what women really need.

advertisement
advertisement
Use Pill Finder Find it Now See Interactions

Pill Identifier on RxList

  • quick, easy,
    pill identification

Find a Local Pharmacy

  • including 24 hour, pharmacies

Interaction Checker

  • Check potential drug interactions
Search the Medical Dictionary for Health Definitions & Medical Abbreviations