"The Centers for Disease Control and Prevention (CDC) is closely following new reports of the mosquito-borne chikungunya (chik-un-GUHN-ya) virus among residents of the French side of St. Martin in the Caribbean. While outbreaks of chikungunya "...
SPORANOX® (itraconazole injection) Injection contains the excipient hydroxypropyl-β-cyclodextrin which produced pancreatic adenocarcinomas in a rat carcinogenicity study. These findings were not observed in a similar mouse carcinogenicity study. The clinical relevance of these findings is unknown. (See PRECAUTIONS: Carcinogenesis, Mutagenesis, and Impairment of Fertility.)
Instruct patients that hearing loss can occur with the use of itraconazole. The hearing loss usually resolves when treatment is stopped, but can persist in some patients. Advise patients to inform their physicians if any hearing loss symptoms occur.
Last reviewed on RxList: 5/18/2009
This monograph has been modified to include the generic and brand name in many instances.
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