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Sprycel Drug Center

Sprycel (dasatinib) is a kinase inhibitor that blocks proteins that signal certain cancer cells to divide. It is used to treat Philadelphia chromosome-positive acute lymphoblastic leukemia (resistant to prior or failed therapy) and chronic, accelerated, or myeloid or lymphoid blast phase Philadelphia chromosome-positive (Ph+) chronic myeloid leukemia (CML) with resistance or intolerance to prior therapy including imatinib. The generic name is dasatinib; Sprycel is not currently available as a generic. Side effects of Sprycel may include headaches, flu-like symptoms, skin rash, mouth sores, weakness, weight loss, muscle and joint discomfort, and gastrointestinal (GI) symptoms (nausea, vomiting, diarrhea or constipation). Severe side effects of Sprycel may occur; rapid or irregular heartbeats, chest pain, GI bleeding (bloody vomit or bloody stools), mental status changes, severe weakness or headaches, shortness of breath, rapid weight gain or swelling (edema) are all reasons that medical care should be sought quickly. This drug interacts with many common medications so the treating physician needs a complete medical and current medication history before prescribing Sprycel to a patient.

Sprycel tablets are available as 20, 50, 70, 80, 100, and 140 mg film-coated tablets. Doses are highly variable and are determined by the disease type, and a physician experienced in treating malignancies refractory to other drug treatments; high doses are 140 mg once per day. The dose, even when adjusted, is still usually only once per day; tablets should be swallowed whole and not chewed. Crushed tablets are capable of causing skin rashes and the drug can be adsorbed; gloves should be used when disposing crushed tablets. Women who are pregnant should avoid any contact with this medication; women who are breastfeeding should not come in contact with this drug.

Our Sprycel Drug Center provides a comprehensive view of available drug information as well as related drugs, user reviews, supplements, and diseases, and conditions.