"The U.S. Food and Drug Administration today approved Iclusig (ponatinib) to treat adults with chronic myeloid leukemia (CML) and Philadelphia chromosome positive acute lymphoblastic leukemia (Ph+ ALL), two rare blood and bone marrow diseases."...
Sprycel Patient Information including If I Miss a Dose
In this Article
- What is dasatinib (Sprycel)?
- What are the possible side effects of dasatinib (Sprycel)?
- What is the most important information I should know about dasatinib (Sprycel)?
- What should I discuss with my health care provider before taking dasatinib (Sprycel)?
- How should I take dasatinib (Sprycel)?
- What happens if I miss a dose (Sprycel)?
- What happens if I overdose (Sprycel)?
- What should I avoid while taking dasatinib (Sprycel)?
- What other drugs will affect dasatinib (Sprycel)?
- Where can I get more information?
What happens if I miss a dose (Sprycel)?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose (Sprycel)?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Overdose symptoms may include some of the serious side effects listed in this medication guide.
What should I avoid while taking dasatinib (Sprycel)?
Avoid taking an antacid within 2 hours before or 2 hours after you take dasatinib. Use only the type of antacid your doctor recommends. Some antacids can make it harder for your body to absorb dasatinib.
Avoid being near people who are sick or have infections. Tell your doctor at once if you develop signs of infection.
Grapefruit and grapefruit juice may interact with dasatinib and lead to potentially dangerous effects. Discuss the use of grapefruit products with your doctor.
What other drugs will affect dasatinib (Sprycel)?
Tell your doctor about all other medicines you use, especially:
- alfentanil (Alfenta), fentanyl (Abstral, Actiq, Fentora, Duragesic, Ionsys, Lazanda, Onsolis);
- bosentan (Tracleer);
- conivaptan (Vaprisol);
- cyclosporine (Gengraf, Neoral, Sandimmune);
- dexamethasone (Cortastat, Dexasone, Solurex, DexPak);
- ergotamine (Ergomar, Cafergot, Migergot);
- imatinib (Gleevec);
- isoniazid (for treating tuberculosis);
- pimozide (Orap);
- rifabutin (Mycobutin), rifampin (Rifadin, Rifater, Rifamate), or rifapentine (Priftin);
- St. John's wort;
- an antibiotic such as clarithromycin (Biaxin), erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin, Pediazole), or telithromycin (Ketek);
- an antidepressant such as nefazodone;
- antifungal medication such as itraconazole (Sporanox), ketoconazole (Nizoral), miconazole (Oravig), or voriconazole (Vfend);
- phenobarbital (Solfoton) and other barbiturates;
- aspirin, or a blood thinner such as warfarin (Coumadin, Jantoven);
- heart or blood pressure medication such as nicardipine (Cardene) or quinidine (Quin-G);
- HIV/AIDS medicine such as atazanavir (Reyataz), delavirdine (Rescriptor), efavirenz (Sustiva), etravirine (Intelence), fosamprenavir (Lexiva), indinavir (Crixivan), nelfinavir (Viracept), nevirapine (Viramune), saquinavir (Invirase), or ritonavir (Kaletra, Norvir);
- medicines to treat narcolepsy, such as armodafinil (Nuvigil) or modafinil (Progivil);
- medication used to prevent blood clots, such as bivalirudin (Angiomax), clopidogrel (Plavix), dalteparin (Fragmin), dipyridamole (Persantine, Aggrenox), enoxaparin (Lovenox), fondaparinux (Arixtra), lepirudin (Refludan), ticlopidine (Ticlid);
- medicines used to prevent organ transplant rejection, such as cyclosporine (Gengraf, Neoral, Sandimmune), sirolimus (Rapamune), or tacrolimus (Prograf);
- seizure medication such as carbamazepine (Carbatrol, Equetro, Tegretol), felbamate (Felbatol), oxcarbazepine (Trileptal), phenytoin (Dilantin), or primidone (Mysoline); or
- stomach acid reducers such as cimetidine (Tagamet), esomeprazole (Nexium), famotidine (Pepcid), lansoprazole (Prevacid), nizatidine (Axid), omeprazole (Prilosec, Zegerid), pantoprazole (Protonix), rabeprazole (Aciphex), or ranitidine (Zantac).
This list is not complete and there are many other drugs that can interact with dasatinib. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you.
Where can I get more information?
Your pharmacist can provide more information about dasatinib.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
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Additional Sprycel Information
- Sprycel Drug Interactions Center: dasatinib oral
- Sprycel Side Effects Center
- Sprycel Overview including Precautions
- Sprycel FDA Approved Prescribing Information including Dosage
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