Brand Names: Starlix

Generic Name: nateglinide (oral) (Pronunciation: na ta GLYE nide)

• What is nateglinide (Starlix)?
• What are the possible side effects of nateglinide (Starlix)?
• What is the most important information I should know about nateglinide (Starlix)?
• What should I discuss with my doctor before taking nateglinide (Starlix)?
• How should I take nateglinide (Starlix)?
• What happens if I miss a dose (Starlix)?
• What happens if I overdose (Starlix)?
• What should I avoid while taking nateglinide (Starlix)?
• What other drugs will affect nateglinide (Starlix)?
• Where can I get more information?

What is nateglinide (Starlix)?

Nateglinide is an oral diabetes medicine that helps control blood sugar levels. This medication helps your body respond better to insulin produced by your pancreas.

Nateglinide is used together with diet and exercise to treat type 2 (non-insulin dependent) diabetes. Other diabetes medicines are sometimes used in combination with nateglinide if needed.

Nateglinide may also be used for purposes other than those listed in this medication guide.

Starlix 120 mg

oblong, yellow, imprinted with STARLIX, 120

Starlix 60 mg

round, pink, imprinted with STARLIX, 60

What are the possible side effects of nateglinide (Starlix)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

• seizure (convulsions); or
• jaundice (yellowing of the skin or eyes).

Less serious side effects may include:

• runny or stuffy nose, sneezing, cough, cold or flu symptoms;
• diarrhea, nausea;
• back pain;
• dizziness; or
• joint pain or stiffness.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about nateglinide (Starlix)?

Do not use this medication if you are allergic to nateglinide, if you have type 1 diabetes, or if you are in a state of diabetic ketoacidosis (call your doctor for treatment with insulin).

Take care not to let your blood sugar get too low, causing hypoglycemia. You may have hypoglycemia if you skip a meal, exercise too long, drink alcohol, or are under stress.

Know the signs of low blood sugar (hypoglycemia) and how to recognize them. Always keep a source of sugar available in case you have symptoms of low blood sugar. Sugar sources include orange juice, glucose gel, candy, or milk. Severe hypoglycemia may cause loss of consciousness, seizures, or death. If you have severe hypoglycemia and cannot eat or drink, use an injection of glucagon. Your doctor can give you a prescription for a glucagon emergency injection kit and tell you how to give the injection.

If your blood sugar gets too high (hyperglycemia), you may feel very thirsty or hungry. You may also urinate more than usual. Call your doctor right away if you have any symptoms of hyperglycemia.

Nateglinide is only part of a complete program of treatment that also includes diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely. Changing any of these factors can affect your blood sugar levels.

It is important to take nateglinide regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.