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Staticin Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

Last reviewed on RxList 6/8/2016

Staticin (erythromycin topical) Solution 1.5% is an antibiotic used for the topical treatment of acne vulgaris. The brand name Staticin is discontinued, but generic versions may be available. Common side effects of Staticin (erythromycin topical) Solution 1.5% include:

  • skin dryness
  • oiliness
  • itching
  • redness
  • tenderness
  • skin sloughing
  • peeling
  • hives, and
  • irritation

Staticin Solution should be applied over the affected area twice a day after the skin is thoroughly washed with warm water and soap and patted dry. Staticin may interact with other drugs. Tell your doctor all medications and supplements you use. During pregnancy, Staticin should be used only if prescribed. It is unknown if this drug passes into breast milk when applied topically. However, this drug passes into breast milk when taken orally. Consult your doctor before breastfeeding.

Our Staticin (erythromycin topical) Solution 1.5% Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is Prescribing information?

The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.

Staticin FDA Prescribing Information: Side Effects
(Adverse Reactions)


In controlled clinical trials, the total incidence of adverse reactions associated with the use of STATICIN (erythromycin topical solution 1.5%) was approximately 13%. These were dryness (7%), oiliness (2%), pruritus (2%), tenderness (2%), desquamation (2%), erythema (1%) and irritation (1%).

The following additional adverse reactions have been reported occasionally: peeling, generalized urticarial reactions and itching.

Read the entire FDA prescribing information for Staticin (Erythromycin Topical Solution 1.5%)

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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