"Feb. 22, 2011 -- The FDA has issued a safety announcement notifying health care professionals that it has updated the pregnancy section of drug labels for the entire class of antipsychotic medications.
Antipsychotic drugs are used to "...
- Clinician Information:
Stelazine Patient Information including How Should I Take
In this Article
- What is trifluoperazine (Stelazine)?
- What are the possible side effects of trifluoperazine (Stelazine)?
- What is the most important information I should know about trifluoperazine (Stelazine)?
- What should I discuss with my healthcare provider before taking oral trifluoperazine (Stelazine)?
- How should I take trifluoperazine (Stelazine)?
- What happens if I miss a dose (Stelazine)?
- What happens if I overdose (Stelazine)?
- What should I avoid while taking trifluoperazine (Stelazine)?
- What other drugs will affect trifluoperazine (Stelazine)?
- Where can I get more information?
What should I discuss with my healthcare provider before taking oral trifluoperazine (Stelazine)?
Trifluoperazine is not for use in psychotic conditions related to dementia. Trifluoperazine may cause heart failure, sudden death, or pneumonia in older adults with dementia-related conditions.
Do not use trifluoperazine if you have liver disease, brain damage, bone marrow depression, a blood cell disorder (such as low platelets or low red or white blood cell counts), or if you are also using large amounts of alcohol or medicines that make you sleepy. Do not use if you are allergic to trifluoperazine or other phenothiazines such as chlorpromazine (Thorazine), fluphenazine (Permitil), perphenazine (Trilafon), prochlorperazine (Compazine, Compro), promethazine (Adgan, Pentazine, Phenergan), or thioridazine (Mellaril).
To make sure you can safely take trifluoperazine, tell your doctor if you have any of these other conditions:
- heart disease high blood pressure, or angina (chest pain);
- severe asthma, emphysema, or other breathing problem;
- a history of seizures;
- adrenal gland tumor (pheochromocytoma);
- Parkinson's disease;
- enlarged prostate or urination problems;
- low levels of calcium in your blood (hypocalcemia);
- past or present breast cancer; or
- if you are pregnant.
Tell your doctor if you will be exposed to extreme heat or cold, or to insecticide poisons while you are taking trifluoperazine.
Taking antipsychotic medication during the last 3 months of pregnancy may cause problems in the newborn, such as withdrawal symptoms, breathing problems, feeding problems, fussiness, tremors, and limp or stiff muscles. However, you may have withdrawal symptoms or other problems if you stop taking your medicine during pregnancy. If you become pregnant while taking trifluoperazine, do not stop taking it without your doctor's advice.
Trifluoperazine can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
Talk with your doctor before giving this medication to a child who has been ill with a fever or flu symptoms.
How should I take trifluoperazine (Stelazine)?
Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results.
Call your doctor if your symptoms do not improve, or if they get worse while taking trifluoperazine.
If you need to have an x-ray or CT scan of your spinal column using a dye that is injected into a vein, you may need to temporarily stop taking trifluoperazine. Be sure the doctor knows ahead of time that you are using this medication.
Do not stop using trifluoperazine suddenly after long-term use, or you could have unpleasant withdrawal symptoms. Ask your doctor how to avoid withdrawal symptoms when you stop using trifluoperazine.
Store at room temperature away from moisture, heat, and light.
Additional Stelazine Information
- Stelazine Drug Interactions Center: trifluoperazine oral
- Stelazine Side Effects Center
- Stelazine FDA Approved Prescribing Information including Dosage
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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