Stimate

Drug Description
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Stimate®
(desmopressin acetate) Nasal Spray, 1.5 mg/mL

DRUG DESCRIPTION

Stimate® (desmopressin acetate) is a synthetic analogue of the natural pituitary hormone 8-arginine vasopressin (ADH), an antidiuretic hormone affecting renal water conservation. Stimate® Nasal Spray contains 1.5 mg/mL desmopressin acetate in an aqueous solution at a pH of approximately 5.0.

Stimate® Nasal Spray's compression pump delivers 0.1 mL (150 mcg) of solution per spray. It is chemically defined as follows:

Mol. Wt. 1183.34       Empirical formula: C46H64N14O12S2 •C2H4O2•3H2O

Stimate® (desmopressin acetate) Structural Formula Illustration

1-(3-mercaptopropionic acid)-8-D-arginine vasopressin monoacetate (salt) trihydrate.

Stimate® Nasal Spray is provided as an aqueous solution for intranasal use.

Each mL contains:  
Active ingredient:
  Desmopressin acetate 1.5 mg
Inactive ingredients:
  Sodium chloride 7.5 mg
  Buffer:
    Citric acid monohydrate 1.7 mg
    Disodium phosphate dihydrate 3.0 mg
  Preservative:
    Benzalkonium chloride 0.1 mg
  Purified water To 1 mL

Last updated on RxList: 4/10/2008

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