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Streptase

Introduction to deep vein thrombosis (DVT)

Arteries have thin muscles within their walls to be able to withstand the pressure of the heart pumping blood to the far reaches of the body. Veins don't have a significant muscle lining, and there is nothing pumping blood back to the heart except physiology. Blood returns to the heart because the body's large muscles squeeze the veins as they contract in their normal activity of moving the body. The normal activities of moving the body returns the blood back to the heart.

There are two types of veins in the leg; superficial veins and deep veins. Superficial veins lie just below the skin and are easily seen on the surface. Deep veins, as their name implies, are located deep within the muscles of the leg. Blood flows from the superficial veins into the deep venous system through small perforator veins. Superficial and perforator veins have one-way valves within them that allow blood to flow only in the direc...

Streptase

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Discontinued Warning IconPlease Note: This Brand Name drug is no longer available in the US.
(Generic versions may still be available.)

Streptase Drug Center

Medical Editor: John P. Cunha, DO, FACOEP

Streptase (streptokinase) is used in the treatment of heart attack or lung blood clots (pulmonary embolism) as well as leg blood clots (deep venous thrombosis-DVT). It is an enzyme. The brand name drug Streptase is no longer available in the U.S. Generic versions may still be available. Common side effects include nausea, dizziness, low blood pressure or mild fever. It can also cause nerve damage.

Streptase (streptokinase) is given by injection by a health care professional. Dose is dependent upon the condition of the patient and response to treatment. Streptase may interact with blood thinners, non-steroidal anti-inflammatory drugs (NSAIDs), or aspirin. Drugs that can reverse effects of streptokinase include aminocaproic acid, aprotinin, and tranexamic acid. Tell your doctor all medications you are taking. Streptase should be given to a pregnant woman only if prescribed. It is not known if this medication passes into breast milk. Consult your doctor before breast-feeding.

Our Streptase (streptokinase) Drug Center provides a comprehensive view of available drug information as well as related drugs, user reviews, supplements, and diseases and conditions articles.

What is Prescribing information?

The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.

Streptase Prescribing Information: Indications & Dosage

Acute Evolving Transmural Myocardial Infarction: Streptase, Streptokinase, is indicated for use in the management of acute myocardial infarction (AMI) in adults, for the lysis of intracoronary thrombi, the improvement of ventricular function, and the reduction of mortality associated with AMI, when administered by either the intravenous or the intracoronary route, as well as for the reduction of infarct size and congestive heart failure associated with AMI when administered by the intravenous route. Earlier administration of Streptokinase is correlated with greater clinical benefit. ...

Read the complete drug monograph for Streptase »

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