Streptase (Streptokinase) Drug Information: Overdosage and Contraindications

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May 27, 2012

Streptase

Deep Vein Thrombosis (DVT) »

Introduction to deep vein thrombosis (DVT)

Arteries have thin muscles within their walls to be able to withstand the pressure of the heart pumping blood to the far reaches of the body. Veins don't have a significant muscle lining, and there is nothing pumping blood back to the heart except physiology. Blood returns to the heart because the body's large muscles squeeze the veins as they contract in their normal activity of moving the body. The normal activities of moving the body returns the blood back to the heart.

There are two types of veins in the leg; superficial veins and deep veins. Superficial veins lie just below the skin and are easily seen on the surface. Deep veins, as their name implies, are located deep within the muscles of the leg. Blood flows from the superficial veins into the deep venous system through small perforator veins. Superficial and perforator veins have one-way valves within them that allow blood to flow only in the direc...

Read the Deep Vein Thrombosis (DVT) article »

Streptase

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Please Note: This Brand Name drug is no longer available in the US.
(Generic versions may still be available.)

OVERDOSE

No Information Provided.

CONTRAINDICATIONS

Because thrombolytic therapy increases the risk of bleeding, Streptase, Streptokinase, is contraindicated in the following situations:

active internal bleeding
recent (within 2 months) cerebrovascular accident, intracranial or intraspinal surgery (see WARNINGS)
intracranial neoplasm
severe uncontrolled hypertension

Streptokinase should not be administered to patients having experienced severe allergic reaction to the product.

Last reviewed on RxList: 10/7/2008
This monograph has been modified to include the generic and brand name in many instances.