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Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

This drug should not be used with certain live bacterial vaccines (e.g., BCG, typhoid) because the vaccines may not be effective. If you have recently received or are planning to receive any vaccinations, tell your doctor or pharmacist before starting streptomycin.

Some products that may interact with this drug include: amphotericin B, "water pills"/diuretics (e.g., hydrochlorothiazide), high doses of aspirin/NSAIDs such as ibuprofen/naproxen.

If your doctor has directed you to take low doses of aspirin to prevent heart attack or stroke (usually at dosages of 81-325 milligrams a day), you should continue to take the aspirin. Consult your doctor or pharmacist for more details.

Although most antibiotics probably do not affect hormonal birth control such as pills, patch, or ring, some antibiotics may decrease their effectiveness. This could cause pregnancy. Examples include rifamycins such as rifampin or rifabutin. Be sure to ask your doctor or pharmacist if you should use additional reliable birth control methods while using this antibiotic.

OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US National Poison Hotline at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms may include: extreme drowsiness, slow/shallow breathing, inability to move.

NOTES: Laboratory and/or medical tests (e.g., kidney tests, hearing tests, streptomycin levels) should be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details.

MISSED DOSE: For the best possible benefit, it is important to receive each scheduled dose of this medication as directed. If you miss a dose, contact your doctor or pharmacist immediately to establish a new dosing schedule.

STORAGE: Not applicable. This medication is given in a hospital and will not be stored at home.

Information last revised January 2011 Copyright(c) 2011 First DataBank, Inc.