Striant (Testosterone) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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May 26, 2012

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Striant

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STRIANT®
(testosterone buccal system) Mucoadhesive

DRUG DESCRIPTION

Striant® (testosterone buccal system) is designed to adhere to the gum or inner cheek. It provides a controlled and sustained release of testosterone through the buccal mucosa as the buccal system gradually hydrates. Insertion of Striant® (testosterone) twice a day, in the morning and in the evening, provides continuous systemic delivery of testosterone.

Striant® (testosterone) is a white to off-white colored, monoconvex, tablet-like, mucoadhesive buccal system. Striant® (testosterone) adheres to the gum tissue above the incisors, with the flat surface facing the cheek mucosa.

The active ingredient in Striant® is testosterone. Each buccal system contains 30 mg of testosterone. Testosterone USP is practically white crystalline powder chemically described as 17-beta hydroxyandrost-4-en-3one.

STRIANT® (testosterone buccal) Structural Formula Illustration

C₁₉H₂₈O₂ M.W.: 288.42

Other pharmacologically inactive ingredients in Striant® (testosterone) are anhydrous lactose NF, carbomer 934P, hypromellose USP, magnesium stearate NF, lactose monohydrate NF, polycarbophil USP, colloidal silicon dioxide NF, starch NF and talc USP.

What are the possible side effects of testosterone buccal system (Striant)?

If you experience any of the following serious side effects, stop using testosterone buccal system and seek emergency medical attention or contact your doctor immediately:

an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
nausea or vomiting;
changes in skin color;
swelling of the ankles or legs;
breathing disturbances, including those associated with sleep;
too frequent or prolonged...

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What are the precautions when taking testosterone (Striant)?

Before using testosterone, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients (such as soy), which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: male breast cancer, prostate cancer.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver problems, prostate problems (e.g., enlarged prostate or benign prostatic hyperplasia-BPH), heart problems (e.g., congestive heart failure, coronary artery disease), kidney problems, swelling (edema), ongoing lung...

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Last reviewed on RxList: 5/19/2009
This monograph has been modified to include the generic and brand name in many instances.