In this Article

• What is mafenide (Sulfamylon Cream)?
• What are the possible side effects of mafenide (Sulfamylon Cream)?
• What is the most important information I should know about mafenide (Sulfamylon Cream)?
• What should I discuss with my health care provider before receiving mafenide (Sulfamylon Cream)?
• How is mafenide used (Sulfamylon Cream)?
• What happens if I miss a dose (Sulfamylon Cream)?
• What happens if I overdose (Sulfamylon Cream)?
• What should I avoid while being treated with mafenide (Sulfamylon Cream)?
• What other drugs will affect mafenide (Sulfamylon Cream)?
• Where can I get more information?

What should I discuss with my health care provider before receiving mafenide (Sulfamylon Cream)?

You should not use this medication if you are allergic to mafenide.

Before using mafenide, tell your doctor if you are allergic to any drugs (especially sulfa drugs), or if you have:

• kidney disease; or
• glucose-6-phosphate dehydrogenase (G6PD) deficiency.

If you have any of these conditions, you may need a dose adjustment or special tests to safely use this medication.

FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant.

It is not known whether mafenide passes into breast milk or if it could harm a nursing baby. Do not receive this medication without telling your doctor if you are breast-feeding a baby.

How is mafenide used (Sulfamylon Cream)?

Your doctor will determine the correct amount and type of this medication to use. You will receive this medication in a hospital or burn unit setting.

Mafenide cream is usually applied to the burn wound once or twice a day. The wound should be kept covered with this medication at all times during treatment.

Mafenide powder is usually mixed together with a saline solution and applied over a gauze dressing using a syringe or irrigation tube. Mafenide is usually applied several times per day in order to keep the bandaging wet.