Brand Names: Sulfamylon

Generic Name: mafenide topical (Pronunciation: MAF en ide)

• What is mafenide (Sulfamylon)?
• What are the possible side effects of mafenide (Sulfamylon)?
• What is the most important information I should know about mafenide (Sulfamylon)?
• What should I discuss with my health care provider before receiving mafenide (Sulfamylon)?
• How is mafenide used (Sulfamylon)?
• What happens if I miss a dose (Sulfamylon)?
• What happens if I overdose (Sulfamylon)?
• What should I avoid while being treated with mafenide (Sulfamylon)?
• What other drugs will affect mafenide (Sulfamylon)?
• Where can I get more information?

What is mafenide (Sulfamylon)?

Mafenide is an antibiotic that fights bacteria in the body.

Mafenide topical (for the skin) is used to prevent infection in severe burn wounds.

Mafenide may also be used for other purposes not listed in this medication guide.

What are the possible side effects of mafenide (Sulfamylon)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Tell your caregivers right away if you have a serious side effect such as:

• pale or yellowed skin, dark colored urine, fever, confusion or weakness;
• chest pain, fast or pounding heartbeats, headache, confusion;
• nausea, vomiting, stomach pain, appetite changes, muscle weakness, bone pain, and weight loss;
• rapid breathing, gasping, or feeling short of breath; or
• severe skin rash, bruising, severe tingling, numbness, or pain.

Less serious side effects may include:

• mild skin rash, redness, or itching; or
• pain or burning of treated skin areas.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

Read the Sulfamylon (mafenide acetate) Side Effects Center for a complete guide to possible side effects »

What is the most important information I should know about mafenide (Sulfamylon)?

You should not receive this medication if you are allergic to mafenide.

Before being treated with mafenide, tell your doctor if you are allergic to any drugs (especially sulfa drugs), or if you have kidney disease or glucose-6-phosphate dehydrogenase (G6PD) deficiency.

Before you are treated with mafenide topical, tell your doctor if you are pregnant or breast-feeding.

Tell your caregivers right away if you have a serious side effect such as pale or yellowed skin, dark colored urine, fever, confusion or weakness, chest pain, fast or pounding heartbeats, confusion, vomiting, appetite changes, muscle weakness, bone pain, rapid breathing, gasping, or feeling short of breath, or severe skin rash with bruising, severe tingling, numbness, or pain.

Follow your doctor's instructions about any restrictions on food, beverages, or activity while you are being treated with mafenide.