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Surmontil

Last reviewed on RxList: 1/19/2016
Surmontil Side Effects Center

Last reviewed on RxList 1/4/2016

Surmontil (trimipramine) is a tricyclic antidepressant used to treat symptoms of depression. Surmontil is available in generic form. Common side effects of Surmontil include dizziness, drowsiness, difficulty urinating, headache, weakness, changes in appetite or weight, dry mouth, blurred vision, ringing in your ears, constipation, diarrhea, tingly feeling, lack of coordination, breast swelling (in men or women), decreased sex drive, impotence, or difficulty having an orgasm.

The usual starting dose of Surmontil is 75 mg/day in divided doses, increased to 150 mg/day. Surmontil may interact with SSRI antidepressants, cimetidine, guanethidine, or heart rhythm medications. Tell your doctor all medications you use. Surmontil should be used only when prescribed during pregnancy. Infants born to mothers who have taken similar medications during pregnancy may develop trouble urinating, lethargy, shaking (tremors), and seizures. It is unknown if this medication passes into breast milk. Consult your doctor before breast-feeding. Withdrawal symptoms may occur if you suddenly stop using this medication.

Our Surmontil (trimipramine) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Surmontil Consumer Information

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.

Call your doctor at once if you have:

  • a feeling that you might pass out;
  • new or worsening chest pain, pounding heartbeats or fluttering in your chest;
  • sudden numbness or weakness, problems with vision, speech, or balance;
  • fever, sore throat;
  • easy bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin;
  • confusion, hallucinations, unusual thoughts or behavior;
  • restless muscle movements in your eyes, tongue, jaw, or neck;
  • painful or difficult urination;
  • extreme thirst with headache, nausea, vomiting, and weakness;
  • seizure (convulsions); or
  • jaundice (yellowing of the skin or eyes).

Other common side effects may include:

  • tingly feeling, weakness, lack of coordination;
  • loss of appetite, constipation, diarrhea;
  • dry mouth, blurred vision, ringing in your ears;
  • breast swelling (in men or women); or
  • decreased sex drive, impotence, or difficulty having an orgasm.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Surmontil (Trimipramine)

Surmontil Professional Information

SIDE EFFECTS

Note: The pharmacological similarities among the tricyclic antidepressants require that each of the reactions be considered when SURMONTIL is administered. Some of the adverse reactions included in this listing have not in fact been reported with SURMONTIL.

Cardiovascular

Hypotension, hypertension, tachycardia, palpitation, myocardial infarction, arrhythmias, heart block, stroke.

Psychiatric

Confusional states (especially the elderly) with hallucinations, disorientation, delusions; anxiety, restlessness, agitation; insomnia and nightmares; hypomania; exacerbation of psychosis.

Neurological

Numbness, tingling, paresthesias of extremities; incoordination, ataxia, tremors; peripheral neuropathy; extrapyramidal symptoms; seizures, alterations in EEG patterns; tinnitus; syndrome of inappropriate ADH (antidiuretic hormone) secretion.

Anticholinergic

Dry mouth and, rarely, associated sublingual adenitis; blurred vision, disturbances of accommodation, mydriasis, constipation, paralytic ileus; urinary retention, delayed micturition, dilation of the urinary tract.

Allergic

Skin rash, petechiae, urticaria, itching, photosensitization, edema of face and tongue.

Hematologic

Bone marrow depression including agranulocytosis, eosinophilia; purpura; thrombocytopenia. Leukocyte and differential counts should be performed in any patient who develops fever and sore throat during therapy; the drug should be discontinued if there is evidence of pathological neutrophil depression.

Gastrointestinal

Nausea and vomiting, anorexia, epigastric distress, diarrhea, peculiar taste, stomatitis, abdominal cramps, black tongue.

Endocrine

Gynecomastia in the male; breast enlargement and galactorrhea in the female; increased or decreased libido, impotence; testicular swelling; elevation or depression of blood sugar levels.

Other

Jaundice (simulating obstructive); altered liver function; weight gain or loss; perspiration; flushing; urinary frequency; drowsiness, dizziness, weakness, and fatigue; headache; parotid swelling; alopecia.

Withdrawal Symptoms

Though not indicative of addiction, abrupt cessation of treatment after prolonged therapy may produce nausea, headache, and malaise.

Read the entire FDA prescribing information for Surmontil (Trimipramine)

Related Resources for Surmontil

Read the Surmontil User Reviews »

© Surmontil Patient Information is supplied by Cerner Multum, Inc. and Surmontil Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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