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The experience with overdose of SYLATRON is limited. Patients who were over dosed experienced the following adverse reactions: severe fatigue, headache, myalgia, neutropenia, and thrombocytopenia. The highest single dose administered was 14 mcg/kg.


SYLATRON is contraindicated in patients with:

  • A history of anaphylaxis to peginterferon alfa-2b or interferon alfa-2b
  • autoimmune hepatitis
  • hepatic decompensation (Child-Pugh score > 6 [class B and C])

Last reviewed on RxList: 1/23/2013
This monograph has been modified to include the generic and brand name in many instances.


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