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home > drugs a-z list > symbyax (olanzapine and fluoxetine) drug center
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Symbyax
How does depression in the elderly differ from depression in younger adults?
Depression in later life frequently coexists with other medical illnesses and disabilities. In addition, advancing age is often accompanied by loss of social support systems due to the death of a spouse or siblings, retirement, or relocation of residence. Because of changes in an elderly person's circumstances and the fact that elderly people are expected to slow down, doctors and family may miss the signs of depression. As a result, effective treatment gets delayed. Many seniors find themselves trying to cope with symptoms that could have been easily treated.
Depression tends to last longer in elderly adults. It doubles their risk of cardiac diseases and increases their risk of death from illness. At the same time, depression reduces an elderly person's ability to rehabilitate.
Studies of nursing home patients with physical illnesses have shown that the pres...
Symbyax
Symbyax Drug Center
Medical Editor: John P. Cunha, DO, FACOEP
Symbyax (olanzapine and fluoxetine hydrochloride) is a combination medication used to treat depression caused by bipolar disorder (manic depression). It may also be used to treat depression when other medications have not worked. Symbyax is combines an atypical antipsychotic, olanzapine, which belongs to the thienobenzodiazepine class, and fluoxetine hydrochloride, which is a selective serotonin reuptake inhibitor. Common side effects include dizziness, drowsiness, diarrhea, dry mouth, constipation, increased appetite, weight gain, or trouble sleeping. Antidepressants can increase the risk of suicidal thoughts and behaviors. There may be an increased risk of serious or fatal side effects (e.g., stroke, heart failure) when used in elderly patients with dementia.
Symbax is taken once/day in the evening, in a 6-mg/25-mg capsule dose. Discuss with your doctor all medications you are taking as Symbax may interact adversely with many different drugs, including: MAO inhibitors, sibutramine, thioridazine, carbamazepine, cimetidine, phenytoin, drugs for anxiety, antipsychotics, antiarrhythmics, antidepressants, fosamprenavir/ritonavir, metoprolol, diuretics, aspirin, antiplatelet drugs, NSAIDs, blood thinners, drugs for high blood pressure, medicines for Parkinson's disease, drugs that increase serotonin, SSRIs, SNRIs, tryptophan, St. John's wort, amphetamines, alcohol, antihistamines, drugs for sleep, muscle relaxants, and narcotic pain relievers. During pregnancy, this medication should be used only when prescribed by a doctor. Babies born to mothers who have used this drug during the last 3 months of pregnancy may develop muscle stiffness or shakiness, drowsiness, feeding/breathing difficulties, or constant crying. If you notice these symptoms in your newborn, tell your doctor. This medication passes into breast milk and may have undesirable effects on a nursing infant. Breast-feeding is not recommended. Do not stop taking this medication without consulting your doctor. Some conditions may worsen when this drug is abruptly stopped.
Our Symbyax Drug Center provides a comprehensive view of available drug information as well as related drugs, user reviews, supplements, and diseases and conditions articles.
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
Symbyax Prescribing Information: Indications & Dosage
Depressive Episodes Associated with Bipolar I Disorder
SYMBYAX is indicated for the acute treatment of depressive episodes associated with Bipolar I Disorder in adults [see Clinical Studies].
Treatment Resistant Depression
SYMBYAX is indicated for the acute treatment of treatment resistant depression (Major Depressive Disorder in adults who do not respond to 2 separate trials of different antidepressants of adequate dose and duration in the current episode) [see Clinical Studies].
Read the complete drug monograph for Symbyax »
What is Symbyax Prescribing Information?
Drug Description - Indications & Dosage - Side Effects & Drug Interactions - Warnings & Precautions - Contraindications - Medication Guide and More
What is Patient information?
Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.
Symbyax Patient Information: Side Effects
Get emergency medical help if you have any of these signs of an allergic reaction: skin rash or hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any new or worsening symptoms such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.
Call your doctor at once if you have any of these serious side effects:
u...Read the complete patient information for Symbyax »
What is Symbyax Patient Information?
Possible Side Effects - Images - What Is - How Should I Take It - What If I Miss a Dose - What Should I Avoid and More
What is Consumer information?
A concise overview of the drug for the patient or caregiver from First DataBank.
Symbyax Consumer Information: Uses
This medication is a combination of 2 drugs, olanzapine (an antipsychotic drug) and fluoxetine (a selective serotonin reuptake inhibitor-SSRI). It is used to treat a certain type of mental/mood disorder (depression associated with bipolar disorder). It is also used to treat depression that has not responded to other medications. This medication may help you sleep, improve your mood, improve your concentration, and decrease nervousness. It works by helping to restore the balance of certain natural substances in the brain (neurotransmitters).
Talk to the doctor about the risks and benefits of...
Read the complete consumer information for Symbyax »
What is Symbyax Consumer Information?
Warnings - Uses - How to Use - Side Effects - Precautions - Drug Interactions and More
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Additional Symbyax Information
Symbyax - User Reviews
Symbyax User Reviews
Now you can gain knowledge and insight about a drug treatment with Patient Discussions.
Here is a collection of user reviews for the medication Symbyax sorted by most helpful.
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