"Sometimes the juice ain't worth the squeeze... especially when combining grapefruit with medicines.
While it can be part of a balanced and nutritious diet, grapefruit can have serious consequences when taken with certain medications. Cu"...
Single 10 mg doses of SYMLIN (83 times the maximum recommended dose of 120 mcg for patients with type 2 diabetes) were administered to 3 healthy volunteers. All 3 individuals reported severe nausea associated with vomiting, diarrhea, vasodilatation, and dizziness. No hypoglycemia was reported. Pramlintide has a short half-life (approximately 48 minutes in healthy individuals). Initiate supportive measures in the case of overdose.
SYMLIN is contraindicated in patients with any of the following:
- serious hypersensitivity reaction to SYMLIN or to any of its product components.
- hypoglycemia unawareness.
- confirmed gastroparesis.
Last reviewed on RxList: 7/14/2014
This monograph has been modified to include the generic and brand name in many instances.
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