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Symlin Patient Information including If I Miss a Dose

What happens if I miss a dose (Symlin)?

Take the missed dose as soon as you remember, but only if you are getting ready to eat a meal. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose (Symlin)?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose may cause diarrhea, vomiting, dizziness, cold sweats, warmth or tingly feeling.

What should I avoid while using pramlintide (Symlin)?

Do not remove pramlintide from an injector pen and put it in a syringe. You may receive too high a dose.

Avoid drinking alcohol. It can lower your blood sugar.

What other drugs will affect pramlintide (Symlin)?

The following drugs can interact with pramlintide. Tell your doctor if you are using any of these:

  • acarbose (Precose) or miglitol (Glyset);
  • disopyramide (Norpace);
  • fluoxetine (Luvox);
  • pentoxyfylline (Trental);
  • propoxyphene (Darvon, Darovcet);
  • diabetes medications you take by mouth;
  • atropine (Atreza, Sal-Tropine), dicyclomine (Bentyl), hyoscyamine (Hyomax), oxybutynin (Ditropan, Oxytrol);
  • an ACE inhibitor such as benazepril (Lotensin), fosinopril (Monopril), enalapril (Vasotec), lisinopril (Prinivil, Zestril), quinapril (Accupril), ramipril (Altace), and others; or
  • cholesterol-lowering medication such as fenofibrate (Lofibra, Fenoglide, TriCor, Lipofen) or gemfibrozil (Lopid).

Using certain medicines can make it harder for you to tell when you have low blood sugar. Tell your doctor if you use any of the following:

  • albuterol (Proventil, Ventolin);
  • clonidine (Catapres); or
  • a beta-blocker such as atenolol (Tenormin, Tenoretic), carvedilol (Coreg), labetalol (Normodyne, Trandate), metoprolol (Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal, InnoPran), sotalol (Betapace), and others.

You may be more likely to have high or low blood sugar if you are using pramlintide with other drugs that raise or lower blood sugar. This includes:

  • isoniazid;
  • probenecid (Benemid);
  • aspirin or other salicylates (including Pepto-Bismol);
  • birth control pills and other hormones;
  • diet pills or medicines to treat asthma, colds or allergies;
  • diuretics (water pills);
  • a monoamine oxidase inhibitor (MAOI);
  • phenothiazines (Compazine and others);
  • steroids (prednisone and others);
  • seizure medicines (Dilantin and others);
  • some nonsteroidal anti-inflammatory drugs (NSAIDs); and
  • sulfa drugs (Bactrim, Gantanol, Gantrisin, Septra, SMX-TMP, and others).

These lists are not complete and other drugs may interact with pramlintide. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about pramlintide.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2013 Cerner Multum, Inc. Version: 3.03. Revision date: 12/15/2010.

Your use of the content provided in this service indicates that you have read,understood and agree to the End-User License Agreement,which can be accessed by clicking on this link.


Side Effects Centers

Symlin - User Reviews

Symlin User Reviews

Now you can gain knowledge and insight about a drug treatment with Patient Discussions.

Here is a collection of user reviews for the medication Symlin sorted by most helpful. Patient Discussions FAQs

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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