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Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your doctor immediately if any of these unlikely but serious side effects occur: purplish-red blotchy spots on the skin, swelling of the ankles/feet, difficulty urinating, vision changes.
Tell your doctor immediately if any of these rare but very serious side effects occur: shortness of breath, mental/mood changes (such as depression, suicidal thoughts/attempts, compulsive behavior including urge to gamble), muscle stiffness, uncontrolled muscle movements, unusual sweating, fast heartbeat, unexplained fever, seizures.
A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US -
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Read the Symmetrel (amantadine hydrochloride) Side Effects Center for a complete guide to possible side effects
PRECAUTIONS: Before taking amantadine, tell your doctor or pharmacist if you are allergic to it; or to rimantadine; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: a certain type of eye disease (untreated closed-angle glaucoma).
Before using this medication, tell your doctor or pharmacist your medical history, especially of: swelling of arms/legs (peripheral edema), heart problems (e.g., congestive heart failure), blood pressure problems (e.g., dizziness when standing), kidney disease, liver disease, mental/mood conditions (e.g., depression, psychosis), seizures, a certain skin condition (eczematoid dermatitis).
This drug may make you dizzy or drowsy or cause blurred vision. Do not drive, use machinery, or do any activity that requires alertness or clear vision until you are sure you can perform such activities safely. Avoid alcoholic beverages.
To minimize dizziness and lightheadedness, get up slowly when rising from a seated or lying position.
If you are taking this medication for Parkinson's disease, be careful not to overdo physical activity as your condition improves because this may increase your risk of falls. Consult your doctor about a plan to gradually increase your physical activity as symptoms improve.
Kidney function declines as you grow older. This medication is removed by the kidneys. Therefore, elderly people may be at a greater risk for side effects while taking this drug.
This medication should be used during pregnancy only if clearly needed. There are rare reports of heart defects in newborns whose mothers took amantadine during pregnancy. Discuss the risks and benefits with your doctor.
This drug passes into breast milk and may have undesirable effects on a nursing infant. Consult with your doctor before breast-feeding.
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Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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