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Synagis

Respiratory syncytial virus (RSV) facts

  • RSV is a highly contagious virus infection that most commonly causes illness during the winter season.
  • Most children who develop an RSV infection have mild symptoms of fever, nasal congestion, and nasal discharge.
  • High-risk groups are more likely to have a more severe disease process, including wheezing (bronchiolitis in infants) and/or pneumonia. Such high-risk groups include premature infants, those children with a compromised immune system, or those with chronic pulmonary disease or congenital/acquired cardiac disease.
  • Supportive care is the mainstay of therapy. For high-risk patients, palivizumab (Synagis) preventative therapy is available.

What is the respiratory syncytial virus (RSV)?

The respiratory syncytial virus (RSV), discovered in 1956, is capable of causing a broad spectrum of illnesses. Older children and adults will commonly e...

Synagis

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Synagis Drug Center

Medical Editor: John P. Cunha, DO, FACOEP

Synagis (palivizumab) is used to prevent serious lung disease caused by respiratory syncytial virus (RSV) in premature infants, and infants born with certain lung disorders or heart disease. It will not treat a child who is already sick with RSV disease. Synagis is a man-made antibody to RSV. Common side effects include diarrhea, fever, cough, earache, runny nose, or pain/redness/swelling at the injection site.

The recommended dose of Synagis is 15 mg per kg of body weight given monthly by intramuscular injection. The first dose of Synagis should be administered prior to commencement of the RSV season and the remaining doses should be administered monthly throughout the RSV season. There may be other drugs that can interact with Synagis. Tell your doctor about all the prescription and over-the-counter medications your child has received. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your child's doctor. Synagis is not indicated for adult usage. It is not known whether Synagis can cause fetal harm or could affect reproductive capacity when administered to a pregnant woman. Because this drug is not for adult use, it is not recommended while breast-feeding.

Our Synagis (palivizumab) Drug Center provides a comprehensive view of available drug information as well as related drugs, user reviews, supplements, and diseases and conditions articles.

What is Prescribing information?

The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.

Synagis Prescribing Information: Indications & Dosage

Synagis is indicated for the prevention of serious lower respiratory tract disease caused by respiratory syncytial virus (RSV) in children at high risk of RSV disease. Safety and efficacy were established in children with bronchopulmonary dysplasia (BPD), infants with a history of premature birth (less than or equal to 35 weeks gestational age), and children with hemodynamically significant congenital heart disease (CHD) [see Clinical Studies].

The following point should be considered when prescribing Synagis:

  • The safety and efficacy of Synagis ...

Read the complete drug monograph for Synagis »

What is Patient information?

Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.

Synagis Patient Information: Side Effects

Get emergency medical help if your child has any of these signs of an allergic reaction: hives; difficult breathing; swelling of the face, lips, tongue, or throat.

Call your doctor at once if your child has a serious side effect such as:

  • high fever, ear pain or drainage, tugging at the ear;
  • warmth or swelling of the ear;
  • crying or fussiness, especially while lying down;
  • change in sleeping patterns;
  • poor feeding or loss of appetite;
  • easy bruising or bleeding; or
  • trouble breathing.
...

Read the complete patient information for Synagis »

What is Consumer information?

A concise overview of the drug for the patient or caregiver from First DataBank.

Synagis Consumer Information: Uses

Palivizumab is used in certain infants and young children to prevent infections of the breathing tubes and lungs that are caused by a certain virus (respiratory syncytial virus-RSV). It is known as a monoclonal antibody, and it works by preventing the growth of RSV. This medication is not used to treat RSV infection.

HOW TO USE: Read the Patient Information Leaflet provided by your doctor or pharmacist before your child starts receiving palivizumab and before each injection. If you have any questions, consult your doctor or pharmacist.

This medic...

Read the complete consumer information for Synagis »

What is Synagis Consumer Information?

Warnings - Uses - How to Use - Side Effects - Precautions - Drug Interactions and More

Synagis - User Reviews

Synagis User Reviews

Now you can gain knowledge and insight about a drug treatment with Patient Discussions.

Here is a collection of user reviews for the medication Synagis sorted by most helpful. Patient Discussions FAQs

Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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