Synarel

Disclaimer

Synarel Consumer

IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.

NAFARELIN ACETATE SPRAY - NASAL

(NAF-a-REL-in AS-e-tate)

COMMON BRAND NAME(S): Synarel

USES: Nafarelin is used in women to treat a condition in which the tissue that normally lines the inside of the uterus grows in the wrong place (endometriosis). This medication helps to decrease the abnormal tissue and also the symptoms of endometriosis (e.g., pelvic pain, painful menstrual cramps, and pain during/after sex).

This medication is also used in children to treat a certain type of early puberty (central precocious puberty, gonadotropin-dependent). It helps to slow the bone aging and height growth rate so that it is near normal and to stop or reverse signs of early puberty (e.g., breast growth in girls, growth of sexual organs in boys).

Nafarelin is a man-made hormone that is similar to a natural hormone made by the body (gonadotropin-releasing hormone-GnRH). It works by decreasing the testosterone hormones in boys and estrogen hormones in women and girls.

HOW TO USE: Read the Patient Information Leaflet, which contains instructions for proper use of this medication. Learn all preparation and usage instructions. Consult your doctor or pharmacist if you have any questions.

Follow the instructions on how to properly prime the bottle if you are using it for the first time.

Gently blow your nose before using this drug. For very young children, it may be necessary to clear the nose with a bulb syringe.

Use this medication usually twice daily (about every 12 hours) as directed by your doctor. If you are using more than 1 spray at a time, wait 30 seconds between each spray. Avoid spraying this medication in your eyes. Also, avoid sneezing during or immediately after using this medication because this may decrease the amount of medication absorbed. Follow the detailed instructions for using the spray and cleaning the spray tip. It is important to clean the spray tip after each use.

Dosage is based on your medical condition and response to therapy. The length of therapy for women taking this medication for endometriosis is 6 months unless otherwise directed by your doctor. The length of therapy for children taking this medication for early puberty depends on when the doctor decides it is appropriate for puberty to resume.

Use this medication regularly to get the most benefit from it. It is important not to miss any doses of this medication, or else this medication may not be effective. To help you remember, use it at the same times each day.

Consult your doctor or pharmacist to find out how long each bottle of the nasal spray should last. Do not use the nasal spray bottle longer, even though there might be some medication left over, because this may result in getting too low a dose. Make sure to get your medication refills a few days early so that you will not run out of your medication.

Do not increase your dose or take this medication more often than prescribed. Your condition will not improve any faster, and the risk of serious side effects may be increased. Also, do not stop this medication without your doctor's approval.

If you need to use a nasal decongestant spray while using this medication, wait at least 2 hours after using this medication before using the decongestant.

When you first start this medication, worsening of symptoms may occur (e.g., increased vaginal bleeding in endometriosis, or vaginal bleeding/period, increase in breast size/pubic hair, oily skin, or body odor in early puberty). Such symptoms should get better after the first month of treatment. Inform your doctor if your symptoms worsen or persist after 2 months.

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