Synarel (Nafarelin Acetate for Central Precocious Puberty) Patient Information: Side Effects and Drug Images at RxList

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May 27, 2012

Synarel

Puberty »

What is puberty?

Puberty is the time at which a growing boy or girl begins the process of sexual maturation. Puberty involves a series of physical stages or steps that lead to the achievement of fertility and the development of the so-called secondary sex characteristics, the physical features associated with adult males and females (such as the growth of pubic hair). While puberty involves a series of biological, or physical, transformations, the process can also have an effect on the psychosocial and emotional development of the adolescent.

When does puberty occur?

The onset of puberty varies among individuals. Puberty usually occurs in girls between the ages of 10 and 14, while in boys it generally occurs later, between the ages of 12 and 16. In some African American girls, puberty begins earlier, at about age 9, meaning that puberty occurs from ages 9 to 14.

Adolescent girls reach puberty today at earlier ages...

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Synarel User Reviews >>

Synarel

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Synarel Patient Information Including Side Effects

Brand Names: Synarel

Generic Name: nafarelin nasal (Pronunciation: NAF a REL in)

What is nafarelin nasal (Synarel)?

Nafarelin nasal is a man-made form of a protein that is like a hormone in the body that helps regulate the menstrual cycle, fertility, and sexual development during puberty.

Nafarelin nasal is used to treat precocious puberty in both male and female children. It is also used to treat endometriosis in women who are 18 years of age or older.

Nafarelin nasal may also be used for other purposes not listed in this medication guide.

What are the possible side effects of nafarelin nasal (Synarel)?

Get emergency medical help if you have any of these signs of a rare side effect called pituitary apoplexy: sudden headache with vision changes, vomiting, confusion, slow heart rate, chest pain, weakness, fainting, or cardiac arrest.

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

heavy or continued menstrual bleeding;
chest pain, shortness of breath;
fast or irregular heartbeats; or
pelvic pain or swelling.

Less serious side effects may include:

mild itching or skin rash;
oily skin or acne, increased body odor;
dandruff;
changes in breast size;
increase in pubic hair growth;
nasal irritation or runny nose;
hot flashes;
mild headache, muscle pain;
mood swings;
white or brownish vaginal discharge;
light and occasional menstrual bleeding;
vaginal dryness; or
changes in sexual desire.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about nafarelin nasal (Synarel)?

This medication can cause birth defects in an unborn baby. Do not use if you are pregnant. Use an effective barrier form of birth control, and tell your doctor if you become pregnant during treatment.

Do not use nafarelin nasal if you have ever had an allergic reaction to nafarelin or similar medicines such as gonadorelin (Factrel). Do not use nafarelin nasal if you are pregnant or breast-feeding, or if you have undiagnosed, abnormal vaginal bleeding.

To be sure this medication is helping your condition, your doctor will need to check your progress on a regular basis, especially during the first 6 to 8 weeks of treatment. It is important that you not miss any scheduled visits to your doctor.

When you first start using nafarelin nasal to treat precocious puberty, you may notice an increase in signs of puberty, such as enlarged breasts or vaginal bleeding. These are normal side effects of this medication during the first month of use. If such pubertal signs continue for longer than 1 month, contact your doctor.

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