Synarel Nasal Solution (Nafarelin Acetate Nasal Solution for Endometriosis) Patient Information: How Should I Take the Drug at RxList

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May 27, 2012

Synarel Nasal Solution

Endometriosis »

What is endometriosis?

Endometriosis is the abnormal growth of cells (endometrial cells) similar to those that form the inside of the uterus, but in a location outside of the uterus. Endometrial cells are cells that are shed each month during menstruation. The cells of endometriosis attach themselves to tissue outside the uterus and are called endometriosis implants. These implants are most commonly found on the ovaries, the Fallopian tubes, outer surfaces of the uterus or intestines, and on the surface lining of the pelvic cavity. They can also be found in the vagina, cervix, and bladder, although less commonly than other locations in the pelvis. Rarely, endometriosis implants can occur outside the pelvis, on the liver, in old surgery scars, and even in or around the lung or brain. Endometrial implants, while they can cause problems, are benign (not cancerous).

Who is affected by endometriosis?

Endometriosis affects w...

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Synarel Nasal Solution

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Synarel Nasal Solution Patient Information including How Should I Take

What should I discuss with my healthcare provider before using nafarelin nasal (Synarel Nasal Solution)?

Do not use nafarelin nasal if you have:

a history of allergic reaction to this medication or to similar medicines such as gonadorelin (Factrel);
undiagnosed, abnormal vaginal bleeding; or
if you are pregnant or breast-feeding.

If you have certain conditions, you may need a dose adjustment or special tests to safely use this medication. Before using nafarelin nasal, tell your doctor if you have:

polycystic ovary disease;
a personal or family history of osteoporosis;
a head cold, allergies, or other causes of a stuffy or runny nose; or
if you smoke or drink large amounts of alcohol.

FDA pregnancy category X. This medication can cause birth defects. Do not use nafarelin nasal if you are pregnant. Tell your doctor right away if you become pregnant during treatment. Use an effective barrier form of birth control (such as a condom or diaphragm with spermicide gel or inserts). Hormonal forms of contraception (such as birth control pills, injections, implants, skin patches, and vaginal rings) may not be effective enough to prevent pregnancy during your treatment.

It is not known whether nafarelin nasal passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I use nafarelin nasal (Synarel Nasal Solution)?

Use this medication exactly as it was prescribed for you. Do not use the medication in larger amounts, or use it for longer than recommended by your doctor.

To use the nasal spray:

Before the first use, prime the spray bottle by pumping it 5 to 10 times until a fine spray appears.
Gently blow your nose to clear any mucus. Uncap the spray bottle.
Insert the tip of the spray bottle into your nostril, pointing it straight upward. Block your other nostril with your finger. Quickly and gently pump the spray bottle one time and sniff gently at the same time. Remove the pump from your nose and tilt your head back slightly for a few seconds.
If using more than one spray per nostril, wait at least 30 seconds between each spray.
Clean the spray bottle tip with a tissue and recap it.

To be sure this medication is helping your condition, your doctor will need to check your progress on a regular basis, especially during the first 6 to 8 weeks of treatment. It is important that you not miss any scheduled visits to your doctor.

When you first start using nafarelin nasal to treat precocious puberty, you may notice an increase in signs of puberty, such as enlarged breasts or vaginal bleeding. These are normal side effects of this medication during the first month of use. If such pubertal signs continue for longer than 1 month, contact your doctor.

It is important to use nafarelin nasal regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.

Store nafarelin nasal at room temperature away from moisture, heat, and light.

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