Synercid (Quinupristin and Dalfopristin) Drug Overview of Side Effects and Precautions for Patients and Caregivers at RxList

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May 27, 2012

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Strep Throat »

What is strep throat?

While many people use the terms sore throat, tonsillitis, and strep throat interchangeably, there are significant clinical differences between these conditions. Understanding the differences can give patients a better idea of how and when to be concerned and when to seek advice from a physician.

Strep throat is only one of many possible causes of throat infection and sore throat. While strep throat is most common in children and adolescents, it can affect people of all ages.

What causes sore throat?

Sore throat has many causes. The most common causes of sore throat are infections of the throat and the surrounding structures. Any inflammation or infection of the pharynx, tonsils, esophagus (the food pipe), or larynx (the top opening part of the windpipe) may cause sore throat.

What are the tonsils and tonsillitis?

The tonsils are red, oval clumps of tissue locat...

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SIDE EFFECTS: Nausea, vomiting, diarrhea, and headache may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if you have any serious side effects, including: joint/muscle pain, redness/swelling/pain/warming of the skin at the injection site, yellowing eyes/skin, blood in the urine.

Get medical help right away if you experience this rare but very serious side effect: chest pain.

This medication may rarely cause a severe intestinal condition (Clostridium difficile-associated diarrhea) due to a type of resistant bacteria. This condition may occur during treatment or weeks to months after treatment has stopped. Do not use anti-diarrhea products or narcotic pain medications if you have any of the following symptoms because these products may make them worse. Tell your doctor immediately if you develop: persistent diarrhea, abdominal or stomach pain/cramping, blood/mucus in your stool.

Use of this medication for prolonged or repeated periods may result in oral thrush or a new vaginal yeast infection. Contact your doctor if you notice white patches in your mouth, a change in vaginal discharge, or other new symptoms.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

PRECAUTIONS: Before using quinupristin/dalfopristin, tell your doctor or pharmacist if you are allergic to it; or to other streptogramin antibiotics (e.g., pristinamycin, virginiamycin); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver problems, high levels of bilirubin in the blood (hyperbilirubinemia).

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

It is not known whether this drug passes into breast milk. Consult your doctor before breast-feeding.