Synvisc (Hylan G-F 20) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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May 26, 2012

Synvisc

Osteoarthritis »

Osteoarthritis facts

Osteoarthritis is a joint inflammation that results from cartilage degeneration.
Osteoarthritis can be caused by aging, heredity, and injury from trauma or disease.
The most common symptom of osteoarthritis is pain in the affected joint(s) after repetitive use.
There is no blood test for the diagnosis of osteoarthritis.
The goal of treatment in osteoarthritis is to reduce joint pain and inflammation while improving and maintaining joint function.

What is osteoarthritis?

Osteoarthritis is a form of arthritis that features the breakdown and eventual loss of the cartilage of one or more joints. Cartilage is a protein substance that serves as a "cushion" between the bones of the joints. Among the over 100 different types of arthritis conditions, osteoarthritis is the most common, affecting over 25 million people in the United Stat...

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Synvisc

Osteoarthritis Overview Slideshow Pictures

Simple Exercises to Relieve OA Pain Slideshow

Rheumatoid Arthritis Slideshow Pictures

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SYNVISC®
(hylan G-F 20)

Caution: Federal law restricts this device to sale by or on the order of a physician (or properly licensed practitioner).

DRUG DESCRIPTION

SYNVISC® (hylan G-F 20) is an elastoviscous high molecular weight fluid containing hylan A and hylan B polymers produced from chicken combs. Hylans are derivatives of hyaluronan (sodium hyaluronate). Hylan G-F 20 is unique in that the hyaluronan is chemically crosslinked. Hyaluronan is a long-chain polymer containing repeating disaccharide units of Na-glucuronate-Nacetylglucosamine.

What are the possible side effects of hylan G-F 20 (Synvisc)?

Notify your doctor immediately if you experience a rare but serious allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives) to hylan G-F 20.

Other less serious side effects may also occur. Talk to your doctor if you experience

temporary pain or swelling of the affected joint;
rash or bruising at the injection site;
headache; or
upset stomach.

Side effects other than those listed here may also occur. Talk to your doctor about any...

Read All Potential Side Effects and See Pictures of Synvisc »

What are the precautions when taking hylan g-f 20 (Synvisc)?

Before using hyaluronate, tell your doctor or pharmacist if you are allergic to it; or to bird proteins, feathers, or egg products; or if you have any other allergies. This product may contain inactive ingredients (such as latex found in the rubber syringe cap of some brands), which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: knee joint infections, skin infections/problems in the area around the injection site, circulation problems in the legs.

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

It is unknown whether this drug passes into breast milk....

Read All Potential Precautions of Synvisc »

Last reviewed on RxList: 7/22/2010
This monograph has been modified to include the generic and brand name in many instances.