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Brand Names: Synvisc

Generic Name: hylan G-F 20 (Pronunciation: HI lan G F 20)

• What is hylan G-F 20 (Synvisc)?
• What are the possible side effects of hylan G-F 20 (Synvisc)?
• What is the most important information I should know about hylan G-F 20 (Synvisc)?
• What should I discuss with my health care provider before using hylan G-F 20 (Synvisc)?
• How should I use hylan G-F 20 (Synvisc)?
• What happens if I miss a dose (Synvisc)?
• What happens if I overdose (Synvisc)?
• What should I avoid while using hylan G-F 20 (Synvisc)?
• What other drugs will affect hylan G-F 20 (Synvisc)?
• Where can I get more information?

What is hylan G-F 20 (Synvisc)?

Hylan G-F 20 is similar to synovial fluid, a substance that occurs naturally in the joints. Synovial fluid acts as a lubricant and shock absorber.

Hylan G-F 20 is injected into the knee joints for the treatment of pain in individuals with osteoarthritis.

Hylan G-F 20 may also be used for purposes other than those listed here.

What are the possible side effects of hylan G-F 20 (Synvisc)?

Notify your doctor immediately if you experience a rare but serious allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives) to hylan G-F 20.

Other less serious side effects may also occur. Talk to your doctor if you experience

• temporary pain or swelling of the affected joint;
• rash or bruising at the injection site;
• headache; or
• upset stomach.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about hylan G-F 20 (Synvisc)?

Talk to your doctor before using hylan G-F 20 if you have an allergy to birds or bird products, feathers, or egg products.