June 24, 2016
Recommended Topic Related To:

Synvisc-One

"The US Food and Drug Administration's (FDA's) Orthopaedic and Rehabilitation Devices Panel of the Medical Devices Advisory Committee voted yesterday to recommend premarket approval of the Cartiva Synthetic Cartilage Implant for use in pati"...

A A A

Synvisc-One




Synvisc-One Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

Last reviewed on RxList 11/23/2015

Synvisc-One (hylan G-F 20) is similar to a substance that occurs naturally in the joints that acts as a lubricant, and is used to treat knee pain caused by osteoarthritis. Synvisc-One is usually given after other arthritis medications have been tried without successful treatment of symptoms. Common side effects of Synvisc-One include injection site reactions (pain, swelling, redness, warmth, stiffness, puffiness, or bruising), headache, muscle pain, trouble walking, fever, chills, nausea, numbness or tingly feeling, dizziness, tired feeling, or itching or skin irritation around the knee.

Synvisc-One is given as an injection into your knee. Your doctor will determine the dose. Synvisc-One may interact with other drugs. Tell your doctor all medications and supplements you use. During pregnancy, Synvisc-One should be used only if prescribed. It is unknown if this drug passes into breast milk. Consult your doctor before breastfeeding.

Our Synvisc-One (hylan G-F 20) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is Patient Information in Detail?

Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.

Synvisc-One in Detail - Patient Information: Side Effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have severe pain or swelling around the knee after the injection.

Less serious side effects may include:

  • warmth, pain, stiffness, swelling, or puffiness where the medicine was injected;
  • muscle pain, trouble walking;
  • fever, chills, nausea;
  • numbness or tingly feeling;
  • headache, dizziness;
  • tired feeling; or
  • itching or skin irritation around the knee.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Synvisc-One (Hylan G-F 20 Single Intra-articular Injection)

What is Patient Information Overview?

A concise overview of the drug for the patient or caregiver from First DataBank.

Synvisc-One Overview - Patient Information: Side Effects

SIDE EFFECTS: See also How to Use section.

Pain, swelling, redness/warmth/bruising at the injection site, or headache may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if you have any serious side effects, including: back pain, severe headache, fast/pounding heartbeat, fever, tingling skin.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Read the entire patient information overview for Synvisc-One (Hylan G-F 20 Single Intra-articular Injection)

What is Prescribing information?

The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.

Synvisc-One FDA Prescribing Information: Side Effects
(Adverse Reactions)

SIDE EFFECTS

Potential Adverse Effects Of The Device On Health

Reported Device-Related Adverse Events

The most commonly reported adverse events associated with Synvisc- One are the following:

A complete list of the frequency and rate of adverse events identified in the clinical study are provided in the Safety section (Table 3).

Potential Adverse Events

The following adverse events are among those that may occur in association with intra-articular injections, including Synvisc-One

  • Arthralgia
  • Joint stiffness
  • Joint effusion
  • Joint swelling
  • Joint warmth
  • Injection site pain
  • Arthritis
  • Arthropathy
  • Gait disturbance

A complete list of the frequency and rate of adverse events identified in the clinical study are provided in the Safety section (Table 2).

Post-Marketing Experience

SYNVISC® (3-injection regimen) post-marketing experience has identified the following systemic events to occur rarely with administration: rash, hives, itching, fever, nausea, headache, dizziness, chills, muscle cramps, paresthesia, peripheral edema, malaise, respiratory difficulties, flushing and facial swelling. There have been rare reports of thrombocytopenia coincident with SYNVISC (3-injection regimen) injection.

Hypersensitivity reactions including anaphylactic reaction, anaphylactoid reaction, anaphylactic shock and angioedema have been reported.

Read the entire FDA prescribing information for Synvisc-One (Hylan G-F 20 Single Intra-articular Injection)

Synvisc-One - User Reviews

Synvisc-One User Reviews

Now you can gain knowledge and insight about a drug treatment with Patient Discussions.

Here is a collection of user reviews for the medication Synvisc-One sorted by most helpful. Patient Discussions FAQs

Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


Arthritis

Get the latest treatment options