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Trientine hydrochloride is N,N'-bis (2-aminoethyl)-1,2-ethanediamine dihydrochloride. It is a white to pale yellow crystalline hygroscopic powder. It is freely soluble in water, soluble in methanol, slightly soluble in ethanol, and insoluble in chloroform and ether.

The empirical formula is C₆H₁₈N₄•2HCl with a molecular weight of 219.2. The structural formula is:

NH₂(CH₂)₂NH(CH₂)₂NH(CH₂)₂NH₂•2HCl

Trientine hydrochloride is a chelating compound for removal of excess copper from the body. SYPRINE¹ (Trientine Hydrochloride) is available as 250 mg capsules for oral administration. Capsules SYPRINE (trientine) contain gelatin, iron oxides, stearic acid, and titanium dioxide as inactive ingredients.

Last reviewed on RxList: 5/19/2009
This monograph has been modified to include the generic and brand name in many instances.