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The esophagus is a tube that connects the mouth to the stomach. It is made of muscles that work to push food toward the stomach in rhythmic waves. Once in the stomach, food is prevented from refluxing (moving back into the esophagus), by a special area of circular muscle located at the junction of the esophagus and stomach, called the lower esophageal sphincter (LES). A pressure difference across the diaphragm, the flat muscle that separates the chest from the abdomen, also tends to keep stomach contents in the stomach.
The stomach combines food, acids, and enzymes together to begin digestion. There are special protective cells that line the stomach to prevent the acid from causing inflammation. The esophagus does not have this same protection; if stomach products reflux back into the esophagus, they can cause inflammation to the lining.
Heartburn is actually a symptom of G...
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Medical Editor: John P. Cunha, DO, FACOEP
Tagamet (cimetidine) is used to treat and prevent certain types of ulcer, and to treat conditions that cause the stomach to produce too much acid. It is also used to treat gastroesophageal reflux disease (GERD), when stomach acid backs up into the esophagus and causes heartburn. Tagamet is in a group of drugs called histamine receptor antagonists. This medication is available in generic form. Common side effects include headache, dizziness, drowsiness, or diarrhea.
Dose of Tagamet depends on the condition being treated and the patient's response to the medication. Tagamet may interact with blood thinners, clopidogrel, phenytoin, nifedipine, metronidazole, propranolol, chlordiazepoxide, lidocaine, diazepam, theophylline, depression or anxiety medications. Tell your doctor all medications you use. Tagamet should be used only when prescribed during pregnancy. This medication passes into breast milk. Consult your doctor before breast-feeding.
Our Tagamet (cimetidine) Drug Center provides a comprehensive view of available drug information as well as related drugs, user reviews, supplements, and diseases and conditions articles.
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
Tagamet (cimetidine) is indicated in:
(1) Short-term treatment of active duodenal ulcer. Most patients heal within 4 weeks and there is rarely reason to use Tagamet (cimetidine) at full dosage for longer than 6 to 8 weeks (see Dosage and Administration-Duodenal Ulcer). Concomitant antacids should be given as needed for relief of pain. However, simultaneous administration of Tagamet (cimetidine) and antacids is not recommended, since antacids have been reported to interfere with the absorption of Tagamet (cimetidine) ...
Read the complete drug monograph for Tagamet »Drug Description - Indications & Dosage - Side Effects & Drug Interactions - Warnings & Precautions - Contraindications - Medication Guide and More
What is Patient information?
Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.
Stop using cimetidine and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:
Read the complete patient information for Tagamet »
Possible Side Effects - Images - What Is - How Should I Take It - What If I Miss a Dose - What Should I Avoid and More
What is Consumer information?
A concise overview of the drug for the patient or caregiver from First DataBank.
Read the complete consumer information for Tagamet »
Warnings - Uses - How to Use - Side Effects - Precautions - Drug Interactions and More
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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