June 29, 2016
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Discontinued Warning IconPlease Note: This Brand Name drug is no longer available in the US.
(Generic versions may still be available.)

How Supplied


Diplococcus pneumoniae

Pneumococcal pneumonia due to susceptible strains.

Streptococcus pyogenes

Group A beta-hemolytic streptococcal infections of the upper respiratory tract.

Injectable benzathine penicillin G is considered by the American Heart Association to be the drug of choice in the treatment and prevention of streptococcal pharyngitis and in long term prophylaxis of rheumatic fever.

Troleandomycin is generally effective in the eradication of streptococci from the nasopharynx. However, substantial data establishing the efficacy of TAO (troleandomycin) in the subsequent prevention of rheumatic fever are not available at present.



Clinical judgment based on the type of infection and its severity should determine dosage within the below listed ranges.

Adults: 250 to 500 mg 4 times a day

Children: 125 to 250 mg (3-5 mg/lb or 6.6 to 11 mg/kg) every 6 hours

When used in streptococcal infection, therapy should be continued for ten days.



TAO (troleandomycin) is supplied as:

Capsules 250 mg: Each capsule contains troleandomycin equivalent to 250 mg of oleandomycin; bottles of 100 (NDC 0049-1590-66).

This monograph has been modified to include the generic and brand name in many instances.

Last reviewed on RxList: 12/8/2004

How Supplied

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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