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Tapazole

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Tapazole

Tapazole®
(methimazole) Tablets, USP

Tapazole

DRUG DESCRIPTION

TAPAZOLE® (methimazole) Tablets, USP (1-methylimidazole-2-thiol) is a white, crystalline substance that is freely soluble in water. It differs chemically from the drugs of the thiouracil series primarily because it has a 5-instead of a 6-membered ring.

Each tablet contains 5 or 10 mg (43.8 or 87.6 μmol) methimazole, an orally administered antithyroid drug.

Each tablet also contains lactose monohydrate, magnesium stearate, starch (corn), pregelatinized starch and talc.

The molecular weight is 114.16, and the molecular formula is C4H6N2S. The structural formula is as follows:

TAPAZOLE® (Methimazole) Structural Formula Illustration

What are the possible side effects of methimazole (Northyx, Tapazole)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using methimazole and call your doctor at once if you have a serious side effect such as:

  • fever, chills, sore throat, body aches, flu symptoms;
  • easy bruising or bleeding, unusual weakness;
  • blood in your urine or stools;
  • severe blistering, peeling, and red skin rash; or
  • nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice...

Read All Potential Side Effects and See Pictures of Tapazole »

What are the precautions when taking methimazole (Tapazole)?

Before taking methimazole, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: blood disorders (such as agranulocytosis, thrombocytopenia), liver disease.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

This medication is not recommended for use during the first 3 months of pregnancy. It should be used only when clearly needed during the last 6 months of pregnancy. Discuss the...

Read All Potential Precautions of Tapazole »

Last reviewed on RxList: 8/6/2012
This monograph has been modified to include the generic and brand name in many instances.

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Tapazole - User Reviews

Tapazole User Reviews

Now you can gain knowledge and insight about a drug treatment with Patient Discussions.

Here is a collection of user reviews for the medication Tapazole sorted by most helpful. Patient Discussions FAQs

Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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