"Vemurafenib (Zelboraf, Roche/Genentech), a BRAF inhibitor marketed for use in the treatment of melanoma, has now shown activity in patients with refractory papillary thyroid cancer.
For the approximately 25% to 50% of patients "...
Tapazole Consumer (continued)
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your doctor immediately if any of these rare but serious side effects occur: yellowing eyes/skin, dark urine, severe stomach/abdominal pain, persistent nausea/vomiting, joint/muscle pain, change in the amount of urine.
This medication may rarely cause very serious blood disorders (such as a low number of red cells, white cells, and platelets), especially during the first few months of treatment. Tell your doctor immediately if you develop any of the following symptoms: signs of infection (such as fever, persistent sore throat), easy bruising/bleeding, unusual tiredness.
A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US -
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Read the Tapazole (methimazole) Side Effects Center for a complete guide to possible side effects
PRECAUTIONS: Before taking methimazole, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: blood disorders (such as agranulocytosis, thrombocytopenia), liver disease.
Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
This medication is not recommended for use during the first 3 months of pregnancy. It should be used only when clearly needed during the last 6 months of pregnancy. Discuss the risks and benefits with your doctor. If you are planning pregnancy, become pregnant, or think you may be pregnant, contact your doctor immediately.
This medication passes into breast milk. Consult your doctor before breast-feeding.
Additional Tapazole Information
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Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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