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Tapazole

Last reviewed on RxList: 9/6/2016
Tapazole Side Effects Center

Last reviewed on RxList 8/26/2015

Tapazole (methimazole) is an anti-thyroid drug used to treat hyperthyroidism (overactive thyroid). Tapazole is also used before thyroid surgery or radioactive iodine treatment. Tapazole is available in generic form. Common side effects of Tapazole include

Tell your doctor if you experience rare but serious side effects of Tapazole including

  • yellowing eyes/skin (jaundice),
  • dark urine,
  • severe stomach or abdominal pain,
  • persistent nausea or vomiting, or
  • changes in the amount of urine.

The initial adult dose of Tapazole is between 15-60 mg/day, depending on the severity of the hyperthyroidism, divided into three doses taken 8 hours apart. Some products that may interact with Tapazole include blood thinners (such as warfarin), digoxin, and theophylline. Tapazole is not recommended for use during the first 3 months of pregnancy and should be used only when prescribed during the last 6 months of pregnancy. Discuss the risks and benefits with your doctor. This medication passes into breast milk. Consult your doctor before breast-feeding.

Our Tapazole Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Tapazole Consumer Information

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using methimazole and call your doctor at once if you have a serious side effect such as:

  • fever, chills, sore throat, body aches, flu symptoms;
  • easy bruising or bleeding, unusual weakness;
  • blood in your urine or stools;
  • severe blistering, peeling, and red skin rash; or
  • nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Less serious side effects may include:

  • headache, drowsiness, dizziness;
  • mild nausea, vomiting, or stomach upset;
  • itching, minor skin rash;
  • muscle, joint, or nerve pain;
  • swelling; or
  • hair loss.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Tapazole (Methimazole)

Tapazole Professional Information

SIDE EFFECTS

Major adverse reactions (which occur with much less frequency than the minor adverse reactions) include inhibition of myelopoieses (agranulocytosis, granulocytopenia, thrombocytopenia, and aplastic anemia), drug fever, a lupus-like syndrome, insulin autoimmune syndrome (which can result in hypoglycemic coma), hepatitis (jaundice may persist for several weeks after discontinuation of the drug), periarteritis, and hypoprothrombinemia. Nephritis occurs very rarely.

Minor adverse reactions include skin rash, urticaria, nausea, vomiting, epigastric distress, arthralgia, paresthesia, loss of taste, abnormal loss of hair, myalgia, headache, pruritus, drowsiness, neuritis, edema, vertigo, skin pigmentation, jaundice, sialadenopathy, and lymphadenopathy.

Read the entire FDA prescribing information for Tapazole (Methimazole)

Related Resources for Tapazole

Read the Tapazole User Reviews »

© Tapazole Patient Information is supplied by Cerner Multum, Inc. and Tapazole Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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