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home > drugs a-z list > tarceva (erlotinib) drug center > tarceva (erlotinib) drug - overdosage and contraindications
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Pancreatic cancer facts
- Most pancreatic cancers are adenocarcinomas.
- Few patients diagnosed with pancreatic cancer have identifiable risk factors.
- Pancreatic cancer is highly lethal.
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- The only curable treatment is surgical removal of all cancer.
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Wh...
Tarceva
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OVERDOSE
Single oral doses of TARCEVA (erlotinib) up to 1,000 mg in healthy subjects and weekly doses up to 1,600 mg in cancer patients have been tolerated. Repeated twice-daily doses of 200 mg single-agent TARCEVA (erlotinib) in healthy subjects were poorly tolerated after only a few days of dosing. Based on the data from these studies, an unacceptable incidence of severe adverse reactions, such as diarrhea, rash, and liver transaminase elevation, may occur above the recommended dose [see DOSAGE AND ADMINISTRATION]. In case of suspected overdose, TARCEVA (erlotinib) should be withheld and symptomatic treatment instituted.
CONTRAINDICATIONS
None
Last reviewed on RxList: 5/7/2010
This monograph has been modified to include the generic and brand name in many instances.
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