"The U.S. Food and Drug Administration today granted accelerated approval to Zykadia (ceritinib) for patients with a certain type of late-stage (metastatic) non-small cell lung cancer (NSCLC).
Zykadia is an anaplastic lymphoma kinase (ALK)"...
Tarceva Patient Information including If I Miss a Dose
In this Article
- What is erlotinib (Tarceva)?
- What are the possible side effects of erlotinib (Tarceva)?
- What is the most important information I should know about erlotinib (Tarceva)?
- What should I discuss with my healthcare provider before taking erlotinib (Tarceva)?
- How should I take erlotinib (Tarceva)?
- What happens if I miss a dose (Tarceva)?
- What happens if I overdose (Tarceva)?
- What should I avoid while using erlotinib (Tarceva)?
- What other drugs will affect erlotinib (Tarceva)?
- Where can I get more information?
What happens if I miss a dose (Tarceva)?
Take the missed dose as soon as you remember (take only on an empty stomach). Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose (Tarceva)?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Overdose symptoms may include severe diarrhea, severe skin rash, dark urine, stomach pain, or jaundice (yellowing of your skin or eyes).
What should I avoid while using erlotinib (Tarceva)?
Avoid taking an antacid within several hours before or after you take erlotinib.
Avoid exposure to sunlight or tanning beds. Erlotinib can cause skin rash, dryness, or other irritation. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.
Avoid using skin products that can cause dryness or irritation, such as acne medications, harsh soaps or skin cleansers, or skin products that contain alcohol.
Avoid smoking. It can make erlotinib less effective.
Grapefruit and grapefruit juice may interact with erlotinib and lead to potentially dangerous effects. Discuss the use of grapefruit products with your doctor. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor.
What other drugs will affect erlotinib (Tarceva)?
Many drugs can interact with erlotinib. Below is just a partial list. Tell your doctor if you are using:
- a blood thinner such as warfarin (Coumadin);
- bosentan (Tracleer);
- conivaptan (Vaprisol);
- dexamethasone (Decadron, Hexadrol);
- imatinib (Gleevec);
- isoniazid (for treating tuberculosis);
- St. John's wort;
- steroid medicine (prednisone and others);
- an antibiotic such as ciprofloxacin (Cipro), clarithromycin (Biaxin), dalfopristin/quinupristin (Synercid), erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin), rifabutin (Mycobutin), rifampin (Rifadin, Rifater, Rifamate), rifapentine (Priftin), or telithromycin (Ketek);
- an antidepressant such as nefazodone;
- antifungal medication such as clotrimazole (Mycelex Troche), itraconazole (Sporanox), ketoconazole (Extina, Ketozole, Nizoral, Xolegal), or voriconazole (Vfend);
- a barbiturate such as butabarbital (Butisol), secobarbital (Seconal), pentobarbital (Nembutal), or phenobarbital (Solfoton);
- heart or blood pressure medication such as diltiazem (Cartia, Cardizem), felodipine (Plendil), nifedipine (Nifedical, Procardia), verapamil (Calan, Covera, Isoptin, Verelan), and others;
- HIV/AIDS medicine such as atazanavir (Reyataz), delavirdine (Rescriptor), efavirenz (Sustiva), etravirine (Intelence), fosamprenavir (Lexiva), indinavir (Crixivan), nelfinavir (Viracept), nevirapine (Viramune), ritonavir (Norvir), or saquinavir (Invirase);
- medicines to treat narcolepsy, such as armodafanil (Nuvigil) or modafanil (Progivil);
- NSAIDs (non-steroidal anti-inflammatory drugs) such as aspirin, ibuprofen (Motrin, Advil), diclofenac (Cataflam, Voltaren), etodolac (Lodine), indomethacin (Indocin), meloxicam (Mobic), nabumetone (Relafen), naproxen (Aleve, Naprosyn), piroxicam (Feldene), and others; or
- seizure medication such as carbamazepine (Carbatrol, Tegretol), felbamate (Felbatol), oxcarbazepine (Trileptal), phenytoin (Dilantin), or primidone (Mysoline).
Where can I get more information?
Your pharmacist can provide more information about erlotinib.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2012 Cerner Multum, Inc. Version: 4.03. Revision date: 12/15/2010.
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Additional Tarceva Information
- Tarceva Drug Interactions Center: erlotinib oral
- Tarceva Side Effects Center
- Tarceva Overview including Precautions
- Tarceva FDA Approved Prescribing Information including Dosage
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