"The U.S. Food and Drug Administration today expanded the approved uses of Abraxane (paclitaxel protein-bound particles for injectable suspension, albumin-bound) to treat patients with late-stage (metastatic) pancreatic cancer.
Targretin Patient Information Including Side Effects
Brand Names: Targretin
Generic Name: bexarotene (Pronunciation: beks AIR oh teen)
- What is bexarotene (Targretin)?
- What are the possible side effects of bexarotene (Targretin)?
- What is the most important information I should know about bexarotene (Targretin)?
- What should I discuss with my healthcare provider before using bexarotene (Targretin)?
- How should I use bexarotene (Targretin)?
- What happens if I miss a dose (Targretin)?
- What happens if I overdose (Targretin)?
- What should I avoid while using bexarotene (Targretin)?
- What other drugs will affect bexarotene (Targretin)?
- Where can I get more information?
What is bexarotene (Targretin)?
The exact way bexarotene works is unknown, but it is believed to inhibit the growth of tumor cells.
Bexarotene is used to treat skin lesions of cutaneous T-cell lymphoma (CTCL) in patients who have not responded to or not tolerated other therapies.
Bexarotene may also be used for purposes other than those listed in this medication guide.
What are the possible side effects of bexarotene (Targretin)?
If you experience any of the following serious side effects, stop taking bexarotene and seek emergency medical attention:
- an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives); or
- symptoms of pancreatitis (inflammation of the pancreas) such as persistent nausea, vomiting, and abdominal or back pain.
Other, less serious side effects may be more likely to occur. Continue to take bexarotene and talk to your doctor if you experience:
- an increase in fats in the blood (blood lipids) such as cholesterol or triglycerides (blood tests will detect this);
- a underactive thyroid (blood tests will detect this);
- blood problems;
- weakness or loss of strength;
- dry skin;
- nausea; or
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.
Read the Targretin (bexarotene) Side Effects Center for a complete guide to possible side effects
What is the most important information I should know about bexarotene (Targretin)?
Avoid prolonged exposure to sunlight or artificial ultraviolet light (e.g. sunlamps). Bexarotene may increase the sensitivity of your skin to sunlight. Use a sunscreen and wear protective clothing when exposure to the sun is unavoidable.
Swallow each capsule whole. Do not chew them, dissolve them in liquid, or allow them to dissolve in your mouth.
Your doctor will want to monitor the levels of lipids (triglycerides and cholesterol) and thyroid hormones in your blood periodically during treatment with bexarotene. Treatment may be necessary if your cholesterol or triglyceride levels become elevated, or if your thyroid hormone levels are low.
Grapefruit and grapefruit juice may interact with bexarotene. The interaction could have potentially dangerous effects. Discuss the use of grapefruit and grapefruit juice with your doctor. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor.
Additional Targretin Information
- Targretin Drug Interactions Center: bexarotene oral
- Targretin Side Effects Center
- Targretin Overview including Precautions
- Targretin FDA Approved Prescribing Information including Dosage
Targretin - User Reviews
Targretin User Reviews
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Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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