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Brand Names: Targretin Topical

Generic Name: bexarotene topical (Pronunciation: beks AIR oh teen)

• What is bexarotene topical (Targretin Gel)?
• What are the possible side effects of bexarotene topical (Targretin Gel)?
• What is the most important information I should know about bexarotene topical (Targretin Gel)?
• Who should not use bexarotene topical (Targretin Gel)?
• How should I use bexarotene topical (Targretin Gel)?
• What happens if I miss a dose (Targretin Gel)?
• What happens if I overdose (Targretin Gel)?
• What should I avoid while using bexarotene topical (Targretin Gel)?
• What other drugs will affect bexarotene topical (Targretin Gel)?
• Where can I get more information?

What is bexarotene topical (Targretin Gel)?

The exact way bexarotene works is unknown, but it is believed to inhibit the growth of tumor cells.

Bexarotene topical is used to treat skin lesions of cutaneous T-cell lymphoma (CTCL) (Stage 1A and 1B) in patients who have not responded to or not tolerated other therapies.

Bexarotene topical may also be used for purposes other than those listed in this medication guide.

What are the possible side effects of bexarotene topical (Targretin Gel)?

Serious side effects are not likely to occur. Stop using bexarotene topical and seek emergency medical attention if you experience an allergic reaction (shortness of breath; closing of your throat; swelling of your lips, face, or tongue; or hives).

You may experience some redness, itching, warmth, swelling, burning, scaling, or other irritation while you are using bexarotene topical. If these side effects are excessive, talk to your doctor. Your doctor may prescribe less frequent applications of bexarotene topical.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about bexarotene topical (Targretin Gel)?

Avoid prolonged exposure to sunlight or artificial ultraviolet light (e.g. sunlamps). Bexarotene topical may increase the sensitivity of your skin to sunlight. Use a sunscreen and wear protective clothing when exposure to the sun is unavoidable.

Do not use bexarotene topical if you are pregnant or if you could become pregnant. Bexarotene topical is in the FDA pregnancy category X. This means that bexarotene topical will cause birth defects in an unborn baby. You must take a pregnancy test and have negative results within one week before starting treatment with bexarotene topical, and a pregnancy test should be repeated monthly during treatment. Bexarotene topical should be started on the second or third day of a normal menstrual period. Also, you will need to use two reliable forms of birth control at the same time for one month before starting treatment with bexarotene topical, during treatment with bexarotene topical, and for at least 1 month following the end of your treatment. If you become pregnant, stop using birth control, or miss your menstrual period, immediately stop using bexarotene topical and notify your doctor. Men using bexarotene topical with sexual partners who are pregnant, possibly pregnant, or who could become pregnant, must use condoms during sexual intercourse while using bexarotene topical and for at least one month after the last dose of bexarotene topical.