"Dec. 18, 2012 -- People who can't get their high blood pressure down with drugs may be helped by a new procedure that deactivates overactive nerves in the kidneys, a small study shows.
The procedure is already available in Europe and "...
Tarka Consumer (continued)
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your doctor immediately if any of these unlikely but serious side effects occur: swelling ankles/feet, unusual tiredness, shortness of breath, fast/irregular/very slow heartbeat, fainting, muscle weakness.
This drug may rarely cause serious (possibly fatal) liver problems. Tell your doctor immediately if you notice any of the following rare but very serious side effects: yellowing eyes/skin, dark urine, severe stomach/abdominal pain, persistent nausea/vomiting.
Tell your doctor immediately if any of these rare but very serious side effects occur: signs of infection (such as fever, persistent sore throat), easy bruising/bleeding, change in the amount of urine.
A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US -
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Read the Tarka (trandolapril and verapamil er) Side Effects Center for a complete guide to possible side effects »
PRECAUTIONS: Before taking this product, tell your doctor or pharmacist if you are allergic to trandolapril or verapamil; or to other ACE inhibitors (such as benazepril, lisinopril); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: certain types of heart rhythm problems (such as second- or third-degree atrioventricular block, sick sinus syndrome unless you have a pacemaker, Wolff-Parkinson-White syndrome, Lown-Ganong-Levine syndrome), a history of an allergic reaction that included swelling of the face/lips/tongue/throat (angioedema).
Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease, kidney disease (such as renal artery stenosis), collagen vascular disease (such as lupus, scleroderma), loss of too much body water (dehydration), certain types of heart problems (such as aortic stenosis, heart failure), certain muscle/nerve disorders (muscular dystrophy, myasthenia gravis), untreated salt imbalance (such as high potassium, low sodium).
This drug may make you dizzy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages.
Losing too much body water (such as too much sweating, diarrhea, or vomiting) can lower your blood pressure and worsen dizziness. Tell your doctor if you have prolonged diarrhea or vomiting. Drink enough fluids during exercise. Consult your doctor for more details.
Before having surgery, tell your doctor or dentist that you are taking this medication.
This product may increase your potassium levels, which could cause side effects. Consult your doctor or pharmacist before using potassium supplements or salt substitutes that contain potassium.
If you have diabetes, this product may cause low blood sugar levels (hypoglycemia) when you first start using it. Check your blood sugar levels regularly as directed by your doctor. Treat symptoms of low blood sugar quickly. Tell your doctor immediately if you have signs of low blood sugar such as nervousness, hunger, and shaking.
Older adults may be more sensitive to the effects of this product, especially dizziness.
This medication is not recommended for use during pregnancy due to the risk for harm to an unborn baby. Consult your doctor for more details. (See also Warning section.)
Verapamil passes into breast milk. It is unknown if trandolapril passes into breast milk. Discuss the risks and benefits with your doctor before breast-feeding.
Additional Tarka Information
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Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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