"The European Medicines Agency's Committee for Medicinal Products for Human Use (CHMP) has recommended the marketing of selexipag (Uptravi, Actelion Registration Ltd) for the treatment of adults with pulmonary arterial hypertension (PAH)./"...
(guanfacine hydrochloride) Tablets
Tenex (guanfacine hydrochloride) is a centrally acting antihypertensive with α2-adrenoceptor agonist properties in tablet form for oral administration.
The chemical name of Tenex (guanfacine hydrochloride) is N-amidino- 2-(2,6-dichlorophenyl) acetamide hydrochloride and its molecular weight is 282.56. Its structural formula is:
Guanfacine hydrochloride is a white to off-white powder; sparingly soluble in water and alcohol and slightly soluble in acetone. The tablets contain the following inactive ingredients:
1 mg - FD&C Red 40 aluminum lake, lactose, microcrystalline cellulose, povidone, stearic acid.
2 mg - D&C Yellow 10 aluminum lake, lactose, microcrystalline cellulose, povidone, stearic acid.
Last reviewed on RxList: 7/18/2013
This monograph has been modified to include the generic and brand name in many instances.
Additional Tenex Information
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