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Tenormin IV Injection

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Tenormin I.V. Injection

Discontinued Warning IconPlease Note: This Brand Name drug is no longer available in the US.
(Generic versions may still be available.)

TENORMIN®
(atenolol) I.V. Injection

DRUG DESCRIPTION

TENORMIN® (atenolol), a synthetic, beta1-selective (cardioselective) adrenoreceptor blocking agent, may be chemically described as benzeneacetamide, 4-[2'-hydroxy-3'- [(1 methylethyl)amino]propoxy]-. The molecular and structural formulas are:

C14H22N2O3

Atenolol (free base) has a molecular weight of 266. It is a relatively polar hydrophilic compound with a water solubility of 26.5 mg/mL at 37°C and a log partition coefficient (octanol/water) of 0.23. It is freely soluble in 1N HCl (300 mg/mL at 25°C) and less soluble in chloroform (3 mg/mL at 25°C).

TENORMIN for parenteral administration is available as TENORMIN I.V. Injection containing 5 mg atenolol in 10 mL sterile, isotonic, citrate-buffered, aqueous solution. The pH of the solution is 5.5-6.5.

Inactive Ingredients: Sodium chloride for isotonicity and citric acid and sodium hydroxide to adjust pH.

Last reviewed on RxList: 9/10/2005
This monograph has been modified to include the generic and brand name in many instances.

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Additional Tenormin I.V. Injection Information

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