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(diethylpropion hydrochloride USP) Immediate-Release 25 mg Tablets
(diethylpropion hydrochloride USP) Controlled-Release 75 mg Tablets
TENUATE® (diethylpropion) is available for oral administration in immediate-release tablets containing 25 mg diethylpropion hydrochloride and in controlled-release tablets containing 75 mg diethylpropion hydrochloride. The inactive ingredients in each immediate-release tablet are: corn starch, lactose, magnesium stearate, pregelatinized corn starch, talc, and tartaric acid. The inactive ingredients in each controlled-release tablet are: carbomer 934P, mannitol, povidone, tartaric acid, zinc stearate. Diethylpropion hydrochloride is a sympathomimetic agent. The chemical name for diethylpropion hydrochloride is 1-phenyl-2-diethyl-amino-1-propanone hydrochloride. Its chemical structure is:
In TENUATE DOSPAN tablets, diethylpropion hydrochloride is dispersed in a hydrophilic matrix. On exposure to water, the diethylpropion hydrochloride is released at a relatively uniform rate as a result of slow hydration of the matrix. The result is controlled release of the anorectic agent.
What are the possible side effects of diethylpropion (Tenuate)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop using diethylpropion and call your doctor at once if you have a serious side effect such as:
- fast, pounding, or uneven heartbeats;
- chest pain, feeling short of breath (even with mild exertion);
- feeling like you might pass out;
- swelling in your ankles or feet;
- confusion, hallucinations, unusual thoughts or behavior;
- seizure (convulsions);
- muscle movements...
What are the precautions when taking diethylpropion (Tenuate)?
Before taking diethylpropion, tell your doctor or pharmacist if you are allergic to it; or to any other sympathomimetic amines (e.g., decongestants such as pseudoephedrine, stimulants such as amphetamine, appetite suppressants such as phentermine); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
This medication should not be used if you have certain medical conditions. Before using diethylpropion, consult your doctor or pharmacist if you have: uncontrolled high blood pressure, glaucoma, history of alcohol/drug abuse, vascular heart disease (e.g., chest pain, heart attack), mental/mood problems (e.g., severe anxiety, bipolar disorder, psychosis,...
Last reviewed on RxList: 12/21/2007
This monograph has been modified to include the generic and brand name in many instances.
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