Endocrine and Urogenital
Female: The most common side effects of androgen therapy are amenorrhea and other menstrual irregularities, inhibition of gonadotropin secretion and virilization, including deepening of the voice and clitoral enlargement. The latter usually is not reversible after androgens are discontinued. When administered to a pregnant woman androgens cause virilization of external genitalia of the female fetus.
Hematologic: Suppression of clotting factors II, V, VII, and X, bleeding in patients on concomitant anticoagulant therapy and polycythemia.
Metabolic: Increased serum cholesterol.
Miscellaneous: Rarely anaphylactoid reactions.
Drug abuse and Dependence
Methyltestosterone Capsules are classified as a schedule III Controlled Substance under the Anabolic Steroids Act of 1990.
Read the Testred (methyltestosterone) Side Effects Center for a complete guide to possible side effects
- Anticoagulants: C-17 substituted derivatives of testosterone, such as methandrostenolone, have been reported to decrease the anticoagulant requirements of patients receiving oral anticoagulants. Patients receiving oral anticoagulant therapy require close monitoring, especially when androgens are started or stopped.
- Oxyphenbutazone: Concurrent administration of oxyphenbutazone and androgens may result in elevated serum levels of oxyphenbutazone.
- Insulin: In diabetic patients the metabolic effects of androgens may decrease blood glucose and insulin requirements.
Read the Testred Drug Interactions Center for a complete guide to possible interactions
Last reviewed on RxList: 11/13/2008
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