Testred (Methyltestosterone) Drug Information: Side Effects and Drug Interactions

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May 27, 2012

Testred

Breast Cancer »

Breast cancer facts

Breast cancer is the most common cancer among American women.
One in every eight women in the United States develops breast cancer.
There are many types of breast cancer that differ in their capability of spreading (metastasize) to other body tissues.
The causes of breast cancer are not yet fully known although a number of risk factors have been identified.
There are many different types of breast cancer.
Breast cancer is diagnosed with physician and self-examination of the breasts, mammography, ultrasound testing, and biopsy.
Treatment of breast cancer depends on the type of cancer and its stage (the extent of spread in the body).

According to the American Cancer society:

Over 200,000 new cases of invasive breast cancer are diagnosed each year.
Nearly 40,000 women will die of breast cancer in 2011.
There are over 2...

Read the Breast Cancer article »

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SIDE EFFECTS

Endocrine and Urogenital

Female: The most common side effects of androgen therapy are amenorrhea and other menstrual irregularities, inhibition of gonadotropin secretion and virilization, including deepening of the voice and clitoral enlargement. The latter usually is not reversible after androgens are discontinued. When administered to a pregnant woman androgens cause virilization of external genitalia of the female fetus.

Male: Gynecomastia, and excessive frequency and duration of penile erections. Oligospermia may occur at high dosages (see CLINICAL PHARMACOLOGY).

Skin and appendages: Hirsutism, male pattern of baldness, and acne.

Fluid and Electrolyte Disturbances: Retention of sodium, chloride, water, potassium, calcium and inorganic phosphates.

Gastrointestinal: Nausea, cholestatic jaundice, alterations in liver function tests, rarely hepatocellular neoplasms and peliosis hepatis (see WARNINGS).

Hematologic: Suppression of clotting factors II, V, VII, and X, bleeding in patients on concomitant anticoagulant therapy and polycythemia.

Nervous System: Increased or decreased libido, headache, anxiety, depression, and generalized paresthesia.

Metabolic: Increased serum cholesterol.

Miscellaneous: Rarely anaphylactoid reactions.

Drug abuse and Dependence

Methyltestosterone Capsules are classified as a schedule III Controlled Substance under the Anabolic Steroids Act of 1990.

DRUG INTERACTIONS

Anticoagulants: C-17 substituted derivatives of testosterone, such as methandrostenolone, have been reported to decrease the anticoagulant requirements of patients receiving oral anticoagulants. Patients receiving oral anticoagulant therapy require close monitoring, especially when androgens are started or stopped.
Oxyphenbutazone: Concurrent administration of oxyphenbutazone and androgens may result in elevated serum levels of oxyphenbutazone.
Insulin: In diabetic patients the metabolic effects of androgens may decrease blood glucose and insulin requirements.

Last reviewed on RxList: 11/13/2008
This monograph has been modified to include the generic and brand name in many instances.