Teveten HCT (Eprosartan Mesylate Hydrochlorothiazide Tablets) Drug Information: Medication Guide and Patient Information

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May 27, 2012

Teveten HCT

Angiotensin Receptor Blockers (ARBs) »

What are angiotensin receptor blockers (ARBs) and how do they work?

The class of drugs called angiotensin receptor blockers (ARBs), as the class name suggests, are drugs that block the action of angiotensin. Specifically, ARBs prevent angiotensin II from binding to the angiotensin II receptor on blood vessels and other tissues.

Angiotensin II is a very potent chemical that causes the muscles surrounding blood vessels to contract, thereby narrowing the blood vessels. Narrowing of blood vessels increases the pressure within the blood vessels and may lead to high blood pressure (hypertension). Reducing the binding and activity of angiotensin II leads to widening (dilation) of blood vessels and reduces blood pressure. By lowering blood pressure against which the heart must pump, the amount of work that the heart must do is reduced. ACE inhibitors also reduce blood pressure in the kidneys, slowing the progression of kidney disease due to high b...

Read the Angiotensin Receptor Blockers (ARBs) article »

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Teveten HCT

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PATIENT INFORMATION

Pregnancy

Female patients of childbearing age should be told about the consequences of exposure to TEVETEN HCT during pregnancy. Discuss treatment options with women planning got become pregnant. Patients should be asked to re port pregnancies to their physicians as soon as possible.

Symptomatic Hypotension: A patient receiving TEVETEN® HCT should be cautioned that lightheadedness can occur, especially during the first days of therapy, and that it should be reported to the prescribing physician. The patient should be told that if syncope occurs, TEVETEN® HCT should be discontinued until the physician has been consulted. All patients should be cautioned that inadequate fluid intake, excessive perspiration, diarrhea, or vomiting can lead to an excessive fall in blood pressure, with the same consequences of lightheadedness and possible syncope.

Potassium Supplements: A patient receiving TEVETEN® HCT should be told not to use potassium supplements or salt substitutes containing potassium without consulting the prescribing physician (see PRECAUTIONS: DRUG INTERACTIONS, Eprosartan Mesylate).

Last reviewed on RxList: 1/30/2012
This monograph has been modified to include the generic and brand name in many instances.