"The cystic fibrosis (CF) drug Orkambi (Vertex Pharmaceuticals) has received a green light from the European Medicines Agency (EMA) Committee for Medicinal Products for Human Use (CHMP).
Orkambi is a fixed-dose oral combination "...
Thalitone Side Effects Center
Medical Editor: John P. Cunha, DO, FACOEP
Thalitone (chlorthalidone) is a thiazide diuretic (water pill) used to treat fluid retention (edema) in people with congestive heart failure, cirrhosis of the liver, or kidney disorders, or edema caused by taking steroids or estrogen. Thalitone is also used to treat high blood pressure (hypertension). Common side effects of Thalitone include dizziness, lightheadedness, headache, blurred vision, loss of appetite, stomach upset, diarrhea, or constipation as your body adjusts to the medication. Other side effects of Thalitone include muscle spasm, decreased sexual ability, or increased sensitivity to the sun.
To treat hypertension the usual starting dose of Thalitone is a single daily dose of 15 mg. If the response is insufficient, the dosage may be increased to 30 mg and then to a single daily dose of 45-50 mg. To treat edema in adults, initial dose is 30 to 60 mg daily or 60 mg on alternate days. Maintenance dose is usually lower. Thalitone may interact with other medicines that make you sleepy (such as cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety), lithium, digoxin, steroids, other blood pressure medications, insulin or oral diabetes medicine. Tell your doctor all medications you use. Thalitone should be used only when prescribed during pregnancy. This drug passes into breast milk. While there have been no reports of harm to nursing infants, consult your doctor before breast-feeding.
Our Thalitone (chlorthalidone) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is Patient Information in Detail?
Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.
Thalitone in Detail - Patient Information: Side Effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using this medication and call your doctor at once if you have any of these serious side effects:
- dry mouth, thirst, nausea, vomiting;
- feeling weak, drowsy, restless, or light-headed;
- fast or uneven heartbeat;
- muscle pain or weakness;
- urinating less than usual or not at all;
- easy bruising or bleeding, unusual weakness;
- red or purple spots on your skin;
- numbness or tingly feeling; or
- nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).
Less serious side effects may include:
- loss of appetite;
- headache; or
- muscle spasm.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may report side effects to FDA at 1-800-FDA-1088.
Read the entire detailed patient monograph for Thalitone (Chlorthalidone)
What is Patient Information Overview?
A concise overview of the drug for the patient or caregiver from First DataBank.
Thalitone Overview - Patient Information: Side Effects
To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
This medication may cause a loss of too much body water (dehydration) and salt/minerals. Tell your doctor right away if you have any symptoms of dehydration or mineral loss, including: extreme thirst, very dry mouth, muscle cramps, weakness, fast/irregular heartbeat, confusion.
Tell your doctor right away if you have any serious side effects, including: fainting, toe/joint pain, change in the amount of urine (not including the normal increase in urine when you first start this drug).
Get medical help right away if you have any very serious side effects, including: decrease in vision, eye pain.
A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US -
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Read the entire patient information overview for Thalitone (Chlorthalidone)
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
Thalitone FDA Prescribing Information: Side Effects
The following adverse reactions have been observed, but there is not enough systematic collection of data to support an estimate of their frequency.
Cardiovascular Reaction: Orthostatic hypotension may occur and may be aggravated by alcohol,barbiturates or narcotics.
Whenever adverse reactions are moderate or severe, chlorthalidone dosage should be reduced or therapy withdrawn.
Read the entire FDA prescribing information for Thalitone (Chlorthalidone)
Additional Thalitone Information
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Find out what women really need.