July 30, 2015
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The Comprehensive List of Antidepressants

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What is depression?

Occasional feelings of sadness or depression are experienced by most people at some point in life. Feeling sad is a normal human response to difficult situations such as loss of a loved one, financial troubles, or problems at home. These feeling usually last for a few days. However, when these feelings turn into intense sadness, or a person feels helpless, worthless, and hopeless, and last for weeks or longer, it could be due to clinical depression. Depression is a common but serious mental illness that affects millions of Americans. The symptoms of depression interfere with daily life and cause significant pain to the patient and their loved ones. Although with proper treatment even severe symptoms of depression can get better, many people never seek treatment due to the societal stigma associated with mental illnesses.

Common symptoms of depression include the following:

  • Sadness, unhappiness
  • Loss of interest in enjoyable activities
  • Anger, frustration, irritability
  • Sleep changes (too much or too little)
  • Feelings of worthlessness
  • Thoughts of death or suicide; suicidal attempts
  • Weight loss or weight gain

What are the classes of available antidepressants?

  • Selective serotonin reuptake inhibitors (SSRIs)
  • Serotonin-norepinephrine reuptake inhibitors (SNRIs)
  • Tricyclic antidepressants (TCAs)
  • Monoamine oxidase inhibitors (MAOIs)
  • Atypical agents
Medically Reviewed by a Doctor on 5/13/2015



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